期刊文献+

MRI扩散成像在帕金森病中的研究进展 被引量:1

Research progress of MRI diffusion imaging in Parkinson’s disease
下载PDF
导出
摘要 帕金森病(Parkinson’s disease,PD)是一种神经系统疾病,具有不断演变的复杂性。临床上除了震颤、僵硬等运动功能障碍之外,还涉及认知、情绪、睡眠、嗅觉和自主神经障碍。其病理改变不仅与路易体聚集和黑质多巴胺能神经元丢失有关,还涉及广泛的神经系统、各种神经递质和多个器官的α-突触核蛋白。帕金森病似乎是由遗传和环境因素相互复杂作用进而影响许多基本细胞所致。
作者 黄小盼 马东辉 王敏 王红 HUANG Xiaopan;MA Donghui;WANG Min;WANG Hong
出处 《新疆医学》 2021年第4期461-463,451,共4页 Xinjiang Medical Journal
基金 新疆维吾尔自治区自然科学基金资助项目(项目编号:2019D01C227)。
  • 相关文献

参考文献3

二级参考文献31

  • 1Zoladz J A,Majerczak J,Zeligo wska E,et al. Moderate-intensityinterval training increases serum brain-derived neurotrophic factorlevel and decreases inflammation in Parkinson's disease patients [J]. JPhysiol Pharmacol,2014,65:441-448.
  • 2Sohn E J,Shin M J,Kim D W,et al. Tat-Fused Recombinant HumanSAG Prevents Dopaminergic Neurodegeneration in a MPTP-InducedParkinson’s Disease Model [J]. Molecules and cells,2014,37(3):226-233.
  • 3Infante J,García Gorostiaga I,Sánchez Juan P,et al. Inflammationrelated genes and the risk of Parkinson’s disease:a multilocus ap-proach [J]. European Journal of Neurology,2008,15(4):431-433.
  • 4Laveti D,Kumar M,Hemalatha R,et al. Anti-inflammatory treatmentsfor chronic diseases:a review [J]. Inflammation & Allergy-Drug Targets(Formerly Current Drug Targets-Inflammation & Allergy),2013,12(5):349-361.
  • 5Hughes AJ,Daniel S E,Kilford L,et al. Accuracy of clinical diagnosisof idiopathic Parkinson's disease:a clinico-pathological study of 100cases [J]. Journal of Neurology,Neurosurgery & Psychiatry,1992,55(3):181-184.
  • 6Hernandes MS,Santos GDR,Café-Mendes CC,et al. Microglial cellsare involved in the susceptibility of NADPH oxidase knockout mice to6-hydroxy-dopamine-induced neurodegeneration [J]. Plo S one,2013,8(9):e75532.
  • 7Mc Geer PL,Mc Geer EG. Glial reactions in Parkinson’s disease [J].Mov Disord,2008,23:474-483.
  • 8Pepys MB,Hirschfield GM,C-reactive protein:a critical update [J].Clin Inves,2003,111:1805-1812.
  • 9Kuo HK,Yen CJ,Chang CH,et al,Relation of C-reactive protein tostroke,cognitive disorders,and depression in the general population:systematic review and meta-analysis [J]. Lancet Neurol,2005,4:371-380.
  • 10Song IU,Chung SW,Kim JS,et al. Association between high-sensi-tivity C-reactive protein and risk of early idiopathic Parkinson’s dis-ease [J]. Neurological Sciences,2011,32(1):31-34.

共引文献27

同被引文献3

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部