Oxidative dual C-H sulfenylation:A strategy for the synthesis of bis(imidazo[1,2-a]pyridin-3-yl)sulfanes under metal-free conditions using sulfur powder

An efficient approach to sulfur-bridged imidazopyridines has been developed under metal-free conditions using inexpensive sulfur powder as the sulfur source.Most appealingly,the reaction can proceed smoothly without addition of any additives,ultimately decreasing the production of chemical waste.The inexpensive and green method should provide a useful strategy for constructing a library of novel and biological interesting heteroaromatic sulfides.