MRI检查DKI、DWI参数对乳腺良、恶性病变的鉴别诊断效能

Effectiveness between DKI and DWI imaging parameters in 3.0 TMRI examination in the differential diagnosis of benign and malignant lesions of breast

目的对比磁共振成像(MRI)检查扩散峰度成像(DKI)、弥散加权成像(DWI)参数对乳腺良、恶性病变的鉴别诊断效能。方法收集我院2018年4月~2020年1月收治的122例乳腺病变患者的临床资料,分为良性组(n=63)和恶性组(n=59)比较良恶性乳腺病变的表观扩散系数(ADC)、扩散峰度值(MK)、平均扩散率(MD)值。并以病理结果为金标准,分析ADC、MK、MD鉴别诊断乳腺良、恶性病变的效能。结果良性组ADC、MD值显著高于恶性组,MK值明显低于恶性组(P<0.05);且乳腺良、恶性病变的形状、边缘及强化方式的差异均有统计学意义(P<0.05)。在ADC、MK、MD中,以MK值鉴别诊断乳腺良、恶性病变的准确率最高,以ADC值最低;联合应用上述参数,可提高鉴别诊断效能,MK+MD+ADC鉴别诊断乳腺良、恶性病变的准确率分别为90.16%。结论MRI检查DKI、DWI成像参数均可有效鉴别诊断乳腺癌,DKI成像参数的诊断效能高于DWI,联合二者可提高鉴别诊断价值。

Objective To compare the effectiveness between diffusion kurtosis imaging(DKI)and diffusion weighted imaging(DWI)parameters in magnetic resonance imaging(MRI)examinations in the differential diagnosis of benign and malignant lesions of breast.Methods The clinical data of 122 patients with breast lesions admitted to our hospital from April 2018 to January 2020 were collected.The values of Apparent diffusion coefficient(ADC),mean kurtosis(MK)and mean diffusivity(MD)values between benign and malignant breast lesions were compared.The pathological results were used as the gold standard to analyze the effectiveness of ADC,MK,and MD in the differential diagnosis of benign and malignant breast lesions.Results The ADC and MD values of the benign group were significantly higher than those of the malignant group(P<0.05).The MK value was significantly lower than that of the malignant group(P<0.05).The difference in the shape,edge and enhancement mode between benign and malignant breast lesions was statistically significant(P<0.05).Among ADC,MK and MD,the accuracy of MK value in the differential diagnosis of breast benign and malignant diseases was the highest,which was 83.61%.And the accuracy of the ADC value was the lowest.The combined application of the above parameters can improve the efficiency of differential diagnosis.The accuracy of MK+MD+ADC in differential diagnosis of benign and malignant breast lesions was 90.16%.Conclusion The DKI and DWI imaging parameters of MRI can effectively differentiate and diagnose breast cancer.The diagnostic efficiency of DKI imaging parameters is higher than that of DWI.Combining them can improve the value of differential diagnosis.