登革热临床特征及病程影响因素分析

Clinical Characteristics and Influencing Factors of Dengue Fever

目的围绕登革热病作为研究重点,观察临床特征,进一步分析其病程影响因素。方法资料来源为2016年福建省福州市长乐区医院的登革热确诊病例,共完成100例登革热病患者的资料收集,以描述性统计研究完成对患者的临床特征分析。借助多元逐步回归模型,实现对登革热病程影响因素的探讨。结果(1)临床症状方面:针对登革热病患者,发热、肌肉关节疼痛为主要临床症状,各占比分别为100%、79%。实验室检查:患者主要表现为白细胞减少、血小板减少,占比分别为81%、69%;其次血清钠降低,占比67%;ALT升高,占比55%。(2)登革热病程影响因素:其主要受到血小板计数的影响。结论当患者被确诊为登革热病后,发热、肌肉关节疼痛为最主要临床症状。登革热病程主要受血小板计数的影响,是最重要的负相关因素。

Objective To observe the clinical features of dengue fever and analyze the influencing factors of its course.Methods The data were collected from the confirmed cases of dengue fever in Changle District Hospital of Fuzhou City,Fujian Province in 2016.A total of 100 cases of dengue fever were collected,and the clinical characteristics of the patients were analyzed by descriptive statistical study.With the help of multiple stepwise recovery model,the influencing factors of dengue fever course were discussed.Results(1)In terms of clinical symptoms:fever,muscle and joint pain were the main clinical symptoms in patients with dengue fever,accounting for 100%and 79%respectively.Laboratory examination:the main manifestations of patients were leukopenia and thrombocytopenia,accounting for 81%and 69%respectively.Secondly,serum sodium decreased,accounting for 67%.ALT increased,accounting for 55%.(2)Influencing factors of dengue fever course:it was mainly affected by platelet count.Conclusion When the patient is diagnosed with dengue fever,fever,muscle and joint pain are the main clinical symptoms.For the course of dengue fever,it is mainly affected by platelet count,which is the most important negative correlation factor.