糖尿病周围神经病变的药物治疗进展

Advances in drug treatment of diabetic peripheral neuropathy

糖尿病周围神经病变以疼痛为主要临床表现。虽治疗方法众多,但大部分治疗方法疗效不佳。药物治疗是基本、简便的治疗方法。本文对糖尿病周围神经病变的药物治疗进行综述,主要介绍抗抑郁药、抗惊厥药、阿片类药物、α-硫辛酸、局部药物、中药,以及治疗新进展,为临床对糖尿病周围神经病变的药物治疗提供参考。

Pain is the major clinical manifestation of diabetic peripheral neuropathy.There are many therapies,but most of them have poor curative effect.Drug treatment is the basic and simple method.Therefore,this article reviews the progress of drug treatment of diabetic peripheral neuropathy,in which the antidepressants,anticonvulsants,opioids,alpha-lipoic acids,topical drugs,traditional Chinese medicine,and the new progresses of treatments are introduced principally,in order to provide a reference for clinical treatment.