响应面法优化分子筛负载磷钨酸催化果糖脱水制5-羟甲基糠醛工艺

Optimization of molecular sieve supported phosphotungstic acid catalyst for fructose dehydrated to 5-hydroxymethylfurfural by response surface methodology

为探讨分子筛负载磷钨酸催化果糖脱水制备5-羟甲基糠醛(5-HMF)的最佳工艺条件,以5-HMF收率为响应值,反应温度、反应时间及催化剂用量为响应变量,运用响应面法的Box-Behnken实验确定了果糖脱水制备5-HMF的最佳工艺条件。结果表明最佳工艺条件为反应温度140.4℃、反应时间2.04 h、催化剂用量0.42 g,在该条件下5-HMF的收率为77.8%,与模型预测值77.5%基本符合,建立的模型准确有效,用于优化果糖脱水制5-HMF工艺条件是可行的。

To explore the optimal process conditions for molecular sieve supported phosphotungstic acid catalyst for fructose dehydrated to 5-hydroxymethylfurfural(5-HMF),the response surface methodology with Box-Behnken experiment was used to determine the optimal process conditions for dehydration of fructose to prepare 5-HMF.The yield of 5-HMF was taken as response value,reaction temperature,reaction time,and catalyst dosage were taken as response variables.The results showed that the reaction temperature was 140.4℃,the reaction time was 2.04 h,and the dosage of the catalyst was 0.42 g.Under these conditions,the yield of 5-HMF was 77.8%,which was consistent with the model predicted value of 77.5%.The established model was accurate and effective and feasible to optimize the process conditions for fructose dehydration to 5-HMF.