摘要
肾移植可改善终末期肾病患者生活质量,是其最有效的治疗方法,但肾移植手术也是膀胱癌的高危因素。膀胱癌是泌尿外科常见的恶性肿瘤,有易复发的特点。卡介苗膀胱灌注治疗是高危非肌层浸润性膀胱癌的一线疗法,能直接杀伤膀胱癌细胞。我们对卡介苗治疗肾移植术后膀胱癌的作用机制及临床应用进行综述,旨在为更好地利用卡介苗辅助治疗肾移植术后膀胱癌提供参考。
Kidney transplantation can improve the quality of life of end-stage renal disease patients and is the most effective treatment.But renal transplantation is also a high risk factor for bladder cancer.Bladder cancer is a common malignant tumor in department of urology.Bacillus Calmette-Guerin intravesical instillation is a first-line therapy for high-risk non muscle invasive bladder cancer,which can directly kill bladder cancer cells.We reviewed the mechanism and clinical application of BCG in the treatment of bladder cancer after renal transplantation,in order to provide references for better utilization of Bacillus Calmette-Guerin in adjuvant treatment of bladder cancer after renal transplantation.
作者
李哲
刘谦
Li Zhe;Liu Qian(Clinical College of the first center of Tianjin Medical University,Tianjin 300000,China;Department of Urology,Tianjin First Central Hospital Affiliated to Nankai University,Tianjin 300192,China)
出处
《中国综合临床》
2021年第4期312-316,共5页
Clinical Medicine of China
基金
国家自然科学基金(51673150)
天津市卫生计生委科技基金(16KG103)。
关键词
卡介苗
膀胱癌
移植
Bacillus Calmette-Guerin
Bladder cancer
Transplant
