非急性期颅内大动脉闭塞治疗现状与展望

Current perspectives and future directions of the treatment for non acute intracranial artery occlusion

非急性期颅内大动脉闭塞可引起严重的神经功能障碍,而且有较高的卒中复发率,目前尚无明确的指南推荐治疗方案。传统的治疗方式有药物治疗、颅内外动脉搭桥治疗以及微创介入血管内再通治疗等。近年来,随着显微吻合技术、神经介入技术的进步及材料学发展,非急性颅内大动脉闭塞的治疗成为了业界广泛关注的热点。现简要综述国内外有关非急性颅内大动脉闭塞的概念、药物治疗、颅内外动脉搭桥治疗以及血管内介入治疗的相关研究进展。

Non-acute intracranial artery total occlusion can lead to severe neurological defect and high recurrence rate of stroke.At present,there is no effective treatment recommended by the guidelines.Traditional treatment methods include medical therapy,extracranial-intracranial bypass surgery and minimally invasive endovascular recanalization therapy.In recent years,with the development of microsurgical vascular anastomosis technique and neurosurgical intervention,and the development of interventional materials,the treatment of non-acute intracranial artery total occlusion has become a hot spots.In this paper,the concept of non on-acute intracranial artery total occlusion,medical therapy,extracranial-intracranial bypass surgery and endovascular interventional therapy are reviewed.