Research progress in decellularized extracellular matrix-derived hydrogels

Decellularized extracellular matrix(dECM)is widely used in regenerative medicine as a scaffold material due to its unique biological activity and good biocompatility.Hydrogel is a three dimensional network structure polymer with high water content and high swelling that can simulate the water environment of human tissues,has good biocompatibility,and can exchange nutrients,oxygen,and waste with cells.At present,hydrogel is the ideal biological material for tissue engineering.In recent years,rapid development of the hydrogel theory and technology and progress in the use of dECM to form hydrogels have attracted considerable attention to dECM hydrogels as an innovative method for tissue engineering and regenerative medicine.