纤维支气管镜灌洗术在支气管扩张合并肺部感染治疗中的疗效评价

Evaluation of the Efficacy of Fiberoptic Bronchoscopy Lavage in the Treatment of Bronchiectasis Complicated with Pulmonary Infection

目的探讨纤维支气管镜灌洗术治疗支气管扩张合并肺部感染的临床疗效。方法于2017年5月—2020年9月便利选取该院254例支气管扩张合并肺部感染患者,应用单盲随机法分为观察组(纤维支气管镜灌洗术+常规治疗)和对照组(常规治疗),各127例,观察两组患者的治疗效果及恢复情况。结果与对照组相比,观察组患者的治疗有效率(96.06%>86.61%)以及治疗后的动脉血氧分压(PaO2)水平[(94.11±6.82)mmHg>(87.09±6.16)mmHg]相对更高,差异有统计学意义(χ^(2)=7.166,t=8.608,P<0.05),而治疗后的动脉血二氧化碳分压(PaCO2)水平[(43.84±6.09)mmHg<(49.71±6.22)mmHg]相对更低,抗生素使用时间[(7.75±1.17)d<(10.23±1.36)d]、症状完全消失时间[(6.83±1.09)d<(9.61±1.15)d]以及住院时间[(13.57±2.61)d<(18.34±2.82)d]相对更短,差异有统计学意义(t=7.599、15.579、19.772、13.990,P<0.05)。结论纤维支气管镜灌洗术治疗支气管扩张合并肺部感染,可以快速减轻患者的临床症状,改善其肺功能。

Objective To investigate the clinical efficacy of fiberoptic bronchoscopy lavage in the treatment of bronchiectasis with pulmonary infection.Methods 254 patients with bronchiectasis and pulmonary infection in the hospital from May 2017 to Sepetember 2020 were conveniently selected and used the single-blind random method,divided into observation group(fiberbronchoscope lavage+conventional treatment)and control group(conventional treatment)with 127 cases in each group.The treatment effect and recovery of the two groups was observed.Results Compared with the control group,the treatment effective rate of the observation group(96.06%>86.61%),and the arterial partial pressure of oxygen(PaO2)level[(94.11±6.82)mmHg>(87.09±6.16)mmHg]after treatment were relatively higher.The difference was statistically significant(χ^(2)=7.166,t=8.608,P<0.05).While the arterial partial pressure of carbon dioxide(PaCO2)level[(43.84±6.09)mmHg<(49.71±6.22)mmHg]was relatively lower,antibiotic use time[(7.75±1.17)d<(10.23±1.36)d],time to complete symptom disappearance[(6.83±1.09)d<(9.61±1.15)d],and hospital stay[(13.57±2.61)d<(18.34±2.82)d]were relatively shorter after treatment,and the difference was statistically significant(t=7.599,15.579,19.772,13.990,P<0.05).Conclusion Fiberoptic bronchoscopy lavage for bronchiectasis combined with pulmonary infection can quickly alleviate the clinical symptoms of patients and improve their lung function.