梗阻性大肠癌行手术治疗的临床疗效及并发症发生情况研究

Clinical efficacy and complications of surgical treatment of obstructive colorectal cancer

目的探究梗阻性大肠癌行手术治疗的临床疗效及并发症发生情况。方法64例梗阻性大肠癌患者,依据手术方案不同分为A组和B组,各32例。A组患者采取开腹手术治疗,B组患者采取腹腔镜手术治疗。比较两组临床治疗效果、手术基本情况及术后并发症发生情况。结果两组治疗有效率比较,差异无统计学意义(P>0.05)。B组手术时间(135.97±18.75)min、术后住院时间(7.57±1.15)d均明显短于A组的(182.35±20.31)min、(14.25±2.10)d,术中出血量(180.74±65.39)ml明显少于A组的(254.36±78.54)ml,差异具有统计学意义(P<0.05)。B组术后并发症发生率为6.25%,显著低于A组的25.00%,差异具有统计学意义(P<0.05)。结论腹腔镜手术治疗梗阻性大肠癌能够取得与开腹手术治疗相当的疗效,但腹腔镜手术时间、术后住院时间更短,术中出血量更少,并发症发生率更低,手术安全性更高,能够有效改善患者预后,可在临床中推广使用。

Objective To investigate the clinical efficacy and complications of surgical treatment of obstructive colorectal cancer.Methods A total of 64 patients with obstructive colorectal cancer were divided into group A and group B according to different surgical methods,with 32 cases in each group.Group A was treated with open surgery,and group B was treated with laparoscopic surgery.The therapeutic effect,basic operation conditions and occurrence of postoperative adverse reactions were compared between the two groups.Results There was no statistically significant difference in effective rate between the two groups(P>0.05).The operation time(135.97±18.75)min and postoperative hospitalization time(7.57±1.15)d of group B were obviously shorter than(182.35±20.31)min and(14.25±2.10)d of group A,and intraoperative blood loss(180.74±65.39)was obviously less than(254.36±78.54)ml of group A.All the difference was statistically significant(P<0.05).The incidence of postoperative adverse reactions 6.25%of group B was significantly lower than 25.00%of group A,and the difference was statistically significant(P<0.05).Conclusion Laparoscopic surgery for obstructive colorectal cancer can achieve the same efficacy as open surgery,but the laparoscopic surgery has shorter operation time and hospitalization time,less intraoperative blood loss,higher surgical safety,and lower incidence of complications,which can effectively improve the prognosis of patients.It is worthy of clinical promotion and application.