摘要
Dear Editor,Induction chemotherapy has been utilized for decades in locally advanced head and neck squamous cell carcinoma(HNSCC).The docetaxel,cisplatin,5-fluorouracil(TPF)regimen is the most recommended induction chemotherapy regimen forHNSCC and oral squamous cell carcinoma(OSCC)[1].However,our initial phase Ⅲ trial failed to demonstrate a significant survival benefit of TPF induction chemotherapy in patients with locally advanced OSCC[2].
基金
supported by the National Natural Science Foundation of China(81972525,81672660)
the Shanghai Municipal Education Commission(17SG18)
the Shanghai Municipal Commission of Health and Family Planning(2018BR41)
the Programof Shanghai Academic/Technology Research Leader(19XD1422300)
Shanghai Jiao Tong University School of Medicine(201916,20191915).