上海市青浦区2012—2016年恶性肿瘤流行特征及生存率分析

Analysis of the epidemiological characteristics and survival rate of cancer in Qingpu District,Shanghai from 2012 to 2016

【目的】分析上海市青浦区2012—2016年居民恶性肿瘤发病、死亡特征及生存率,为后续肿瘤防治提供科学依据。【方法】根据上海市恶性肿瘤病例报告登记系统收集的恶性肿瘤发病和死亡资料,分别计算上海市青浦区恶性肿瘤粗发病率、粗病死率、标化率、前10位恶性肿瘤发病和死亡顺位。采用寿命表法计算生存率,根据同期简略寿命表中的生存率,用EdererⅡ法计算1~5年相对生存率。运用Joinpoint软件计算年度变化百分比(APC),分析发病及死亡变化趋势。【结果】2012—2016年上海市青浦区共报告新发恶性肿瘤病例10 893例,粗发病率为464.68/10万(男性为502.06/10万,女性为428.57/10万),标化发病率为224.61/10万(男性为235.52/10万,女性为217.98/10万)。全区共报告5 820人死于恶性肿瘤,恶性肿瘤粗病死率为248.28/10万(男性为321.92/10万,女性为177.13/10万),标化病死率为97.08/10万(男性为133.14/10万,女性为66.38/10万)。上海市青浦区2012年诊断的恶性肿瘤患者5年标化相对生存率较高的为乳腺癌(87.03%)、中枢神经系统肿瘤(73.62%)和结直肠癌(58.22%);5年标化相对生存率较低的为胰腺癌(3.76%)、食管癌(10.55%)以及肝癌(15.79%)。【结论】肺癌、消化系统恶性肿瘤(包括胃癌、结直肠癌)是威胁青浦区居民健康的主要癌种,虽然乳腺癌、中枢神经系统肿瘤、结直肠癌生存率已达到或接近发达国家水平,但青浦区整体恶性肿瘤生存率较全市低,有待进一步改善。

[Objective]To analyze the incidence and death characteristics of cancer and survival rate of residents in Qingpu District,Shanghai from 2012 to 2016,and to provide a scientific basis for subsequent cancer prevention and treatment.[Methods]The malignant tumor incidence and death data were collected by the Shanghai Malignant Tumor Case Registration System.Based on these data,the crude incidence and mortality rate of cancer,the standardlized rate,the orderof incidence and death ofthe top 10cancers,and the overall survival rate were calculatedusing thelife table method.The relative survivalratefor l to 5 years was calculated usingthe EdererIl method acordling to survival probability inthe abbreviated life table for the same period.The annual percentage change(APC)was calculated by Joinpoint software,and the trend ofmorbidity and mortality was analyzed.[Results]A total of10893 new malignant tumor cases were diagnosed in the region from 2012to 2016.The crude incidence rate of cancer in the whole region was 464.68/100000(502.06/100000 for men and 428.57/100000 for women),and the standardized incidence rate was 224.61/100000(235.52/100000 for men,and 217.98/100000 for women).A total of 5820 people died of cancer,the crude mortality rate of cancer in the whole region was 248.28/100000(321.92/100000 for men and 177.13/100000 for women),and the standardized mortality rate was 97.08/100000(133.14/100000 for men and 66.38/100000 for women).Patients with malignant tumors diagnosed in Qingpu District in 2012 showed higher 5-year relative survival for breast cancer(87.03%),malignant tumors of brain and central nervous system(73.62%),and colorectal cancer(58.22%).A relative low 5-year survival rate was observed in patients with pancreatic cancer(3.76%),esophageal cancer(10.55%),and liver cancer(15.79).[Conclusion]Lung cancer and malignant tumors of the digestive system(including gastric cancer and colorectal cancer)are the main types of cancer threatening the health of residents in Qingpu District.The survival rates of breast cancer,malignant tumors of brain and central nervous system,and colorectal cancer have reached or approached the level of developed countries.However,the overall survival rate of malignant tumors in Qingpu District is lower than that in the city,and needs to be further improved.