摘要
发展了一种对环境友好的乳酸促进的酰胺与胺的氨解的新方法,该方法能够成功合成一系列芳香、脂肪类酰胺和脲的衍生物.该方法最显著的特征是催化剂廉价易得、无挥发性溶剂、底物转化率高及产物提纯操作简单.
An environmentally benign protocol for the transamidation of carboxamides with amines using lactic acid as a green catalyst has been developed.The method has been successfully applied to the synthesis of a wide range of aromatic and aliphatic amides and ureas.The reaction has the advantages of the ready accessibility of the catalyst,solvent-free condition,efficient transformation and green processing.
作者
刘巨艳
赵聪颖
Liu Juyan;Zhao Congying(Tianjin Key Laboratory of Structure and Performance for Functional Molecules,College of Chemistry,Tianjin Normal University,Tianjin 300387)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2021年第6期2310-2318,共9页
Chinese Journal of Organic Chemistry
基金
天津市自然科学基金(No.12JCZDJC34300)
大学生创业训练(No.201447)资助项目。
关键词
乳酸
酰胺
脲
氨解
lactic acid
carboxamide
urea
transamidation
