树脂与高强纤维牙周夹板修复牙周炎合并牙缺失的效果对比

Comparison of the effect of resin and high-strength fiber periodontal splints in repairing periodontitis with loss of teeth

目的探讨树脂夹板与高强纤维牙周夹板在牙周炎合并牙缺失患者中的修复效果,以期为临床治疗方法的选择提供参考。方法选取2016年8月—2019年12月金华市中心医院收治的牙周炎合并牙缺失患者86例,按随机数字表法将其分为对照组和观察组,每组各43例。对照组采用树脂夹板治疗,观察组采用高强纤维牙周夹板治疗。比较2组患者临床疗效,可溶性细胞间黏附分子-1(soluble intercellular adhesion molecule-1,sICAM-1)、白介素-1β(IL-1β)、降钙素原(PCT)水平,骨保护素(osteoprotegerin,OPG)、碱性磷酸酶(alkaline phosphatase,ALP)、Runt相关转录因子2(recombinant runt related transcription factor 2,Runx2)、骨钙素(osteocalcin,OCN)水平,并发症发生情况及患者满意度。结果观察组总有效率[95.35%(41/43)]明显高于对照组[79.07%(34/43),P<0.05];治疗后,观察组sICAM-1、IL-1β及PCT水平均明显低于对照组,OPG、ALP、Runx2及OCN水平均明显高于对照组(均P<0.05);治疗后,观察组并发症总发生率[9.30%(4/43)]明显低于对照组[27.91%(12/43),P<0.05];2组患者总满意度比较差异无统计学意义(P=0.058)。结论高强纤维牙周夹板治疗牙周炎合并牙缺失的临床疗效优于树脂夹板,可有效减轻患者炎症反应,改善骨代谢及牙周组织状况,且患者满意度较高。

Objective To explore the repair effect of resin splint and high-strength fiber periodontal splint in patients with periodontitis and tooth loss,in order to improve the reference for the choice of clinical treatment.Methods Total 86 patients with periodontitis and missing teeth admitted to Jinhua Central Hospital from August 2016 to December 2019 were selected and divided into control group and observation group according to the random number table method,with 43 patients in each group.The control group was treated with resin splint and the observation group was treated with high strength fiber periodontal splint.The clinical efficacy of patients,the levels of soluble intercellular adhesion molecule-1(sICAM-1),interleukin-1(IL-1),procalcitonin(PCT),osteocalcin(OPG),alkaline phosphatase(ALP),runt-relat-ed transcription factor 2(Runx2),osteocalcin(OCN),complications and patient satisfaction were compared between the two groups.Results The total effective rate of the observation group[95.35%(41/43)]was significantly higher than that of the control group[79.07%(34/43),P<0.05)].After treatment,the levels of sICAM-1,IL-1βand PCT in the observation group were significantly lower than those in the control group,and the levels of OPG,ALP,Runx2 and OCN in the observation group were significantly higher than those in the control group(all P<0.05).After treatment,the total incidence of complications in the observation group[9.30%(4/43)]was significantly lower than that in the control group[27.91%(12/43),P<0.05],there was no statistically significant difference in total satisfaction between the two groups(P=0.058).Conclusion The clinical efficacy of high-strength fiber periodontal splint in the treatment of periodontitis combined with tooth loss is better than resin splint,which can effectively reduce the inflammatory response of patients,ameliorate bone metabolism and periodontal tissue,and the patients have a High degree of satisfaction.