神经调控在昏迷患者促醒中的研究进展

The Research Progress of Neuromodulation on Wake-promoting in Patients with Disorders of Consciousness

意识障碍严重影响患者的生命状态和生活质量。随着国内外医学技术的进步,意识障碍患者康复促醒技术也不断发展,包括药物治疗、针刺、高压氧治疗、神经调控治疗等,但疗效不一。本文综述了各种中枢及外周神经调控技术在昏迷促醒中的临床应用及其治疗机制,并简要总结了本团队目前在外周神经调控促进昏迷患者苏醒的相关工作。

Disorders of consciousness(DoC)seriously affect patients’life state and quality of life.With the progress of medical technology at home and abroad,the rehabilitation techniques for patients with DoC are also evolving,including drug therapy,acupuncture,hyperbaric oxygen therapy,neuromodulation techniques,and so on.This article reviewed the clinical application and treatment mechanism of various central and peripheral neuromodulation techniques in wake-promoting of patients with DoC,and briefly summarized the current progress of our team on peripheral neuromodulation to promote awakening from coma in patients with DoC.