酒精性心肌病合并心房颤动的临床特征及影响因素分析

Atrial Fibrillation in Patients with Alcoholic Cardiomyopathy:Clinical Characteristics and Risk Factors

【目的】探讨酒精性心肌病(ACM)合并心房颤动(AF)的患者的临床特征,分析各特征与ACM患者发生AF的相关性。【方法】回顾性分析2013年1月至2020年4月期间于中山大学附属第三医院心血管内科住院的ACM患者42例及ACM合并AF(ACM-AF)患者17例为研究对象,收集患者的临床资料、实验室指标及超声心动图检查结果,比较其临床特征,并采用多因素Logistic回归分析研究ACM患者发生AF的相关影响因素。【结果】单因素分析显示,ACM-AF组与ACM组在年龄[(56.82±9.48)岁vs.(50.55±10.60)岁,P=0.038]、左心房内径[(48.29±8.76)mm vs.(44.38±5.03)mm,P=0.035]和血肌酐值[80(73~95.45)μmol/L vs.98.5(84~108.25)μmol/L,P=0.032]方面的差异具有统计学意义(P<0.05)。多因素Logistic回归分析发现,年龄和左心房内径与ACM患者发生AF相关,而血肌酐值不是影响ACM患者发生AF的相关因素。【结论】年龄和左心房内径是ACM患者发生AF的影响因素。

【Objective】To explore the clinical characteristics of alcoholic cardiomyopathy(ACM)combined with atrial fibrillation(AF)and risk factors for AF in ACM patients.【Methods】A retrospective analysis was performed on 42 cases of ACM(ACM group)and 17 cases of ACM combined with AF(ACM-AF group)hospitalized in our hospital from January 2013 to April 2020.The clinical data,laboratory findings and echocardiographic results were compared between ACM group and ACM-AF group.Multivariate Logistic regression analysis was used to detect the risk factors for AF in ACM patients.【Results】Univariate analysis showed significant difference in age[(56.82±9.48)years vs.(50.55±10.60)years,P=0.038],left atrial diameter[(48.29±8.76)mm vs.(44.38±5.03)mm,P=0.035]and serum creatinine[80(73~95.45)μmol/L vs.98.5(84~108.25)μmol/L,P=0.032]between ACM-AF group and ACM group(P<0.05).Multivariate Logistic regression analysis revealed that age and left atrial diameter were the influencing factors of AF in ACM patients(P<0.05),while serum creatinine has no effect on the incidence of AF in ACM patients(P>0.05).【Conclusion】The older age and enlarged left atrial diameter are the risk factors for AF in patients with ACM.