王秀云教授治疗HPV持续性感染经验撷菁

Highlights of Professor WANG Xiuyun’s Experience in Treating Persistent HPV Infection

宫颈癌是发病率较高的恶性肿瘤,严重威胁女性生命安全,而宫颈高危型人乳头瘤病毒(HPV)持续性感染是促使子宫颈癌发生的最主要因素。临床上对一过性HPV感染可观察,随访。对于持续性HPV感染,西医主要应用干扰素治疗或物理、手术疗法及应用疫苗防治本病,但仍有许多患者应用这些疗法效果不理想。王秀云教授临证治疗本病,辨证论治,认为本病病机为正气不足,房事不洁,湿毒侵袭。治疗以中西医结合之法,中医采用益气健脾、扶正祛湿、清热解毒中药内服之法,方药选用自拟扶正祛毒汤,配合干扰素外用治疗HPV持续性感染,临床效果较好。

Cervical cancer is a malignant tumor with a high incidence,which seriously threatens the safety of women’s lives,and persistent high-risk cervical papillomavirus infection is the most important factor that promotes the occurrence of cervical cancer. Clinically,transient HPV infection can be observed and followed up. For persistent HPV infections,Western medicine mainly uses interferon therapy or physical and surgical therapies and vaccines to prevent and treat the disease,but there are still many patients who use these therapies to achieve unsatisfactory results. Professor WANG Xiuyun treats this disease clinically and treats it based on syndrome differentiation. She believes that the pathogenesis of this disease is deficiency of the vital-Qi,unclean sex,and damp poisoning. The treatment is combined with traditional Chinese and Western medicine. The traditional Chinese medicine adopts the method of oral administration of nourishing Qi and strengthening spleeny,strengthening the vitality and removing dampness,clearing away heat and detoxification. The prescription is self-made Fuzheng Qudu Decoction(扶正祛毒汤),combined with external application of interferon to treat persistent HPV infection,and the clinical effect is good.