常熟市成人血脂异常与糖尿病关系研究

Relationship between dyslipidemia and diabetes mellitus in adults in Changshu

目的探讨常熟市成人血脂异常和糖尿病的关系,为预防和控制糖尿病的发生发展,制定防治策略和措施提供科学依据。方法采用多阶段整群随机抽样方法,随机抽取常熟市6个乡镇/街道≥18岁的成人居民进行一对一面对面问卷调查并体检,分析血脂异常和糖尿病的关系。结果共对11 809名居民进行了调查,男性4776人,女性7 033人,平均年龄(59.46±11.93)岁;调查居民中有6 366人血脂异常,血脂异常率为53.91%,其中总胆固醇(TC)异常率为28.91%,总甘油三酯(TG)异常率为37.14%,高密度脂蛋白胆固醇(HDL-C)异常率为7.53%;成人居民中糖尿病患者1 416人,糖尿病患病率为11.99%。多因素Logistic回归分析结果显示血脂异常、TG异常和HDL-C异常者的糖尿病患病风险分别是正常人的1.351、1.320、1.629倍,TG每增加1个标准差,糖尿病风险增加21.9%,HDL-C每增加1个标准差,糖尿病患病风险降低22.0%。结论常熟市成人血脂异常和糖尿病密切相关,应加强血脂的常规检测,预防及控制糖尿病的发生发展。

Objective Changshu City,so as to provide scientific basis for preventing and controlling the occurrence and development of diabetes mellitus and formulation of prevention strategies.MethodsMulti-stratified clustering random sampling method was used to randomly sample residents aged ≥18 years from 6 townships/streets in Changshu City for one-to-one face-to-face questionnaire survey and physical examination,to analyze the relationship between dyslipidemia and diabetes mellitus.Results(59.46±11.93)years old. There were 6 366 people with dyslipidemia,and the rate of dyslipidemia was 53.91%,including28.91% of total cholesterol(TC),37.14% of total triglyceride(TG),and 7.53% of high density lipoprotein cholesterol(HDL-C). There were 1 416 diabetic patients in adult residents,and the prevalence of diabetes mellitus was 11.99%. Multivariate Logistic regression analysis showed that the risk of diabetes mellitus in people with dyslipidemia,abnormal TG and abnormal HDL-C was 1.351,1.320 and 1.629 times higher than the normal people,each 1 standard deviation increase in TG was associated with a 21.9% increase in diabetes mellitus risk,and each 1 standard deviation increase in HDL-C was associated with a 22.0% decrease in diabetes mellitus risk.ConclusionDyslipidemia in adults in Changshu City is closely related to diabetes mellitus. Routine detection of blood lipids should be strengthened to prevent and control the occurrence and development of diabetes mellitus.