胰腺癌影像学研究现状及热点的文献计量与可视化分析

Bibliometric and visualization analysis of current status and hotspots of pancreatic cancer imaging research

目的了解胰腺癌影像学的研究现状及热点。方法检索Web of Science核心数据库中2001—2020年期间胰腺癌影像学研究的相关文献,采用CiteSpace软件对检索结果进行文献计量学分析。结果本研究检索到胰腺癌影像学研究领域文献共2111篇。共被引文献的聚类有19个:血管切除、不可逆电穿孔、自身免疫性胰腺炎、散发胰腺癌、肌少症、胰腺、立体定向体部放疗、转移性胰腺癌、家族性胰腺癌、腹部超声、成纤维细胞、早期诊断、生存时间趋势、影像组学、胰腺炎、吉西他滨、同步放化疗、新辅助化疗、微泡。2016年以后出现的突发性关键词有4个:FOLFIRINOX、骨骼肌、肌少症、纹理分析。研究热点关键词聚类有17类:预后、细针抽吸、正电子发射断层扫描、血管侵犯、血管生成、不可切除、肝移植、扩大胰腺切除术、移植、紫杉醇、转移性结直肠癌、结直肠癌、微卫星稳定、影像组学、医院容积、隐匿转移、危险因素。结论采用影像组学的方法去研究胰腺癌的预后、危险因素和定量肌少症或许是胰腺癌影像研究的趋势。

Objective To investigative current status and hotspot issues of pancreatic cancer imaging research.Methods The literatures focusing on pancreatic cancer and published from 2001 to 2020 were retrieved from the core database of Web of Science.The quantitative analysis of literatures was then conducted by using the CiteSpace software based on the bibliometric method.The research trend was then summarized systematically and the potential research fronts and focuses were explored.Results A total of 2111 articles in the field of pancreatic cancer imaging research were retrieved.The clustering of co-citation of pancreatic cancer included vascular resection,irreversible electroporation,autoimmune pancreatitis,sporadic pancreatic cancer,sarcopenia,pancreas,stereotactic body radiation therapy,metastatic pancreatic cancer,familial pancreatic cancer,abdominal ultrasonography,fibroblast,early diagnosis,time trends in survival,radiomics,pancreatitis,gemcitabine,concurrent chemoradiotherapy,adjuvant chemotherapy,and microbubbles.The burst keywords in the field of pancreatic cancer after 2016 included FOLFIRINOX,skeletal muscle,sarcopenia,and texture analysis.The hot keywords clustering had prognosis,fine needle aspiration,positron emission tomography,vascular invasion,angiogenesis,unresectable,liver transplant,extend pancreatectomy,transplantation,paclitaxel,metastatic colorectal cancer,colorectal cancer,microsatellite stable,radiomics,hospital volume,occult metastasis,risk factor.Conclusion It might be the trend of imaging research to study the prognosis,risk factors,and quantitative sarcopenia of pancreatic cancer by using radiomics.