清肺化痰方治疗矽肺急性加重期疗效观察

目的观察清肺化痰方治疗矽肺急性加重期(痰热壅肺证)患者的疗效。方法矽肺急性加重期(痰热壅肺证)患者100例,随机分为观察组与对照组各50例。对照组予以西药(哌拉西林他唑巴坦针)治疗,观察组在对照组基础上加用清肺化痰方治疗;两组均治疗10 d,比较两组疗效,结果观察组与对照组总有效率分别92.00%,84.00%,差异有统计学意义(P<0.05)。治疗后两组FEWFVC、FEVi均有改善,且观察组优于对照组,差异有统计学意义(P<0.05)。结论清肺化痰方对矽肺急性加重期(痰热壅肺证)患者有较好的疗效,可以改善肺功能。

Objective To observe the clinical effect of Qingfei Huatan prescription in treating patients with silicosis in acute exacerbation stage(phlegm-heat obstructing lung syndrome).Methods 100 patients were randomly divided into treatment group and control group with 50 cases each.The control group was treated with Western medicine(Piperacillin Tazobactam needle),and the treatment group was treated with Qingfei Huatan Empirical Prescription on the basis of the control group.Results The total effective rate of the treatment group and the control group were 92.00%and 84.00%respectively,the difference was statistically significant(P<0.05),the pulmonary function was improved in FEVi/FVC(%)and FEVi in the treatment group and the control group after treatment,and the difference was statistically significant(P<0.05).After 10 days of treatment,DLCO SB(%)of the two groups were observed.There was no significant difference between the two groups(P>0.05).Conclusion Qingfei Huatan precription has good clinical effect on silicosis patients in acute exacerbation stage(phlegm-heat obstmeting lung syndrome),and it can improve lung function.