孤立性肺结节影像学特征与临床病理相关性分析

目的探讨孤立性肺结节(SPN)的临床、影像学特征与病理诊断的相关性,并分析SPN恶性的危险因素:方法回顾性分析296例手术切除且有明确病理诊断的肺结节患者的临床特征(性别、年龄、吸烟史、肿瘤史)及CT影像学特征(位置、结节直径、边界、纯磨玻璃结节、混合磨玻璃结节、实性结节、钙化、支气管充气征、血管集束征、空泡征、胸膜凹陷征、毛刺、分叶).结果296例肺结节中,良性64例(21.6%),恶性232例(78.4%)。多因素Logistic回归分析显示,患者性别、年龄、结节长径、pGGN、mGGN、胸膜凹陷征、毛刺、分叶是判断SPN恶性的独立因素(P<0.05)。结论患者年龄、结节直径、胸膜凹陷征、结节密度、毛刺征是判断SPN恶性的危险因素。

Objective To study the clinical and imaging characteristics of solitary pulmonary nodules(SPN)and their corresponding pathological diagnosis.Methods 296 patients of surgically resected pulmonary nodules with clear pathological diagnosis were selected to retrospectively analyze the clinical characteristics(gender,age,smoking history,history of tumor),CT imaging characteristics(nodules location,nodal length to diameter,boundary,p GGN,m GGN,solid nodules,calcification,air-filled bronchi),bloodvessels,cluster sign,cavitation character,burr,lobulated sign,pleural sag.Results Among 296 pulmonary nodules,64 cases(21.6%)were benign and 232 cases(78.4%)were malignant.Multiple Logistic regression analysis showed that gender,age,length of nodules,P GGN,M GGN,pleural depression,burr,and lobules were independent factors to determine the benign and malignant SPN(P<0.05).Conclusion Age,nodule length,pleural depression,nodule density and burr are the risk factors for malignant SPN.