摘要
We show that superoscillating light fields,created using the method of optical eigenmodes,enable more efficient multiphoton-mediated cell transfection.Chinese hamster ovary cells are transfected with a plasmid and exhibit expression of DsRed-Mito in the mitochondria.We demonstrate an efficiency improvement of 35%compared to the diffraction-limited spot.This opens up new vistas for nanoscale localized cell transfection.
