播散性荚膜组织胞浆菌感染继发噬血细胞综合征1例

One case report of hemophagocytic syndrome secondary to disseminated Histoplasma capsulatum infection

噬血细胞综合征(hemophagocytic syndrome,HPS)是由多种因素引起的淋巴细胞、组织细胞非恶性过度活化、增殖,并分泌大量炎性因子,进而引起机体一种严重的炎症反应,临床分为原发性HPS和获得性HPS[1]。原发性HPS常见于儿童,继发性HPS以成人居多。感染、风湿性疾病、肿瘤等是引起继发性HPS常见原因。HPS患者若未及时干预,病死率极高[2]。