21242例急性呼吸道感染住院患儿肺炎衣原体分析情况探析

Analysis of Chlamydia Pneumoniae in 21242 Hospitalized Children With Acute Respiratory Tract Infection

目的分析21242例急性呼吸道感染(acute respiratory infection,ARTI)住院患儿肺炎衣原体情况。方法选择2015年1月—2019年12月儿科住院部呼吸科住院的ARTI患儿21242例作为研究对象,采集次日清晨空腹静脉血,分析2015—2019年肺炎衣原体阳性检出率,分析不同性别及不同年龄段肺炎衣原体阳性检出率。结果2015年肺炎衣原体阳性检出率低于2016年、2017年、2018年、2019年,差异有统计学意义(χ^(2)=9.285、124.676、24.943、161.357,P=0.002、0.000、0.000、0.000);2015—2019年男性患儿肺炎衣原体阳性总检出率高于女性患儿,差异有统计学意义(χ^(2)=4.272,P=0.039);<1岁年龄段肺炎衣原体阳性检出率低于≥1且<3岁年龄段,差异有统计学意义(χ^(2)=4.039,P=0.045);<1岁年龄段肺炎衣原体阳性检出率低于≥3且<5岁年龄段,但二者差异无统计学意义(χ^(2)=0.591,P=0.442);<1岁年龄段肺炎衣原体阳性检出率低于≥5岁年龄段,但二者差异无统计学意义(χ^(2)=2.416,P=0.120)。结论肺炎衣原体是引发ARTI的主要病原体,感染率逐年上升,男性患儿阳性检出率较高,在临床鉴别诊断中需给予重视。

Objective To analyze the situation of chlamydia pneumoniae in 21242 hospitalized children with acute respiratory infection(ARTI).Methods From January 2015 to December 2019,21242 ARTI children hospitalized in respiratory department of pediatric inpatient department of our hospital were selected as research objects,and fasting venous blood was collected the next morning to analyze the positive detection rate of chlamydia pneumoniae from 2015 to 2019,and to analyze the positive detection rate of chlamydia pneumoniae of different genders and different ages.Results The positive rate of chlamydia pneumoniae in 2015 was lower than that in 2016,2017,2018 and 2019,with statistical difference(χ^(2)=9.285,124.676,24.943,161.357,P=0.002,0.000,0.000,0.000).From 2015 to 2019,the positive rate of chlamydia pneumoniae in male children was higher than that in female children,with statistical difference(χ^(2)=4.272,P=0.039).The positive detection rate of chlamydia pneumoniae in the age group of less than 1 year was lower than that of≥1 and less than 3 years old group,the difference was statistically significant(χ^(2)=4.039,P=0.045);the positive detection rate of chlamydia pneumoniae in the age group of less than 1 year was lower than≥3 and less than 5 years old group,but the difference between the two was not statistically significant(χ^(2)=0.591,P=0.442);the positive detection rate of chlamydia pneumoniae of less than 1 year old was lower than≥5 years old,but the difference between the two groups was not statistically significant(χ^(2)=2.416,P=0.120).Conclusion Chlamydia pneumoniae is the main pathogen causing ARTI,the infection rate is increasing year by year,and the positive detection rate of male children is high,which should be paid attention to in clinical differential diagnosis.