拉贝洛尔联合硝苯地平对妊高症患者的临床治疗效果研究

Research of Labetalol Combined with Nifedipine on the Clinical Treatment Effect of Patients with Pregnancy Hypertension Syndrome

观察拉贝洛尔联合硝苯地平治疗妊高症的临床效果。选取81例患者妊娠合并高血压患者,按照奇偶数法分为对照组与观察组。对照组40例,给予硫酸镁、硝苯地平治疗,观察组41例,给予硝苯地平、拉贝洛尔治疗,对比两组的临床治疗效果。两组治疗前的舒张压、收缩压、24 h蛋白尿含量比较无显著差异(P>0.05)。两组治疗后的舒张压、收缩压、24 h蛋白尿含量低于治疗前,观察组治疗后的舒张压、收缩压、24 h蛋白尿含量显著低于对照组(P<0.05)。两组的剖宫产率、早产率差异不显著(P>0.05)。观察组的胎盘早剥率、产后出血率、胎儿窘迫率、新生儿窒息率显著少于对照组(P<0.05)。对妊娠合并高血压患者采用硝苯地平、拉贝洛尔联合治疗的效果显著,母婴结局理想。

The research observes the clinical effect of labetalol combined with nifedipine on patients with pregnancy hypertension syndrome.81 patients with pregnancy hypertension syndrome are selected,and they are divided into control group and observation group according to the odd and even numbers.40 patients in control group receive magnesium sulfate and nifedipine treatment,and 41 patients in observation group receive nifedipine and labetalol treatment.Clinical treatment effect of two groups is compared.There is no statistically significant difference in diastolic blood pressure,systolic pressure and 24 h proteinuria content before treatment of two groups(P>0.05).The diastolic blood pressure,systolic pressure and 24 h proteinuria content of two groups after treatment are lower than before treatment,and those of observation group are significantly lower than control group(P<0.05).There is no statistically significant difference in cesarean section and preterm birth rates between two groups(P>0.05).The placental abruption rate,postpartum hemorrhage rate,fetal distress rate and neonatal asphyxia rate of observation group are significantly less than control group(P<0.05).Treatment of labetalol combined with nifedipine on the treatment of patients with pregnancy-induced hypertension syndrome has significant effect,and the maternal and child outcome is ideal.