乳腺癌患者康复期体力恢复不足的影响因素分析

Influence factors of insufficient physical recovery in breast cancer patients during rehabilitation

目的研究乳腺癌患者康复期体力恢复不足的影响因素。方法选取2016年1月—2018年12月在湖北省荆州市松滋市中医院行乳腺癌手术后接受定期随访的116例患者作为研究对象,对所有患者进行国际体力活动问卷(IPAQ-SF)评估,并按照结果将所有患者分为不足组(26例)和良好组(90例),比较两组患者的临床特征,并进行多因素分析。结果有26例(22.41%)患者体力活动不足,63例(54.31%)适中,27例(23.28%)活跃。三类患者的静坐时间、活动时间、总体力活动消耗量、中高强度活动天数比较,差异有统计学意义(P<0.05)。单因素分析结果显示,不足组与良好组年龄≥50岁、体重指数(BMI)≥24 kg/m2、TNM分期为Ⅲ~Ⅳ期、接受化疗、癌因性疲劳、患侧淋巴结水肿患者比例比较,差异有统计学意义(P<0.05)。多因素分析结果显示,年龄≥50岁(β=1.915,OR=6.789,95%CI=1.131~40.752)、BMI≥24 kg/m2(β=2.420,OR=11.246,95%CI=1.889~66.952)、TNM分期Ⅲ~Ⅳ期(β=2.504,OR=12.234,95%CI=2.379~62.913)、接受化疗(β=1.736,OR=5.674,95%CI=1.324~24.316)、癌因性疲劳(β=1.812,OR=6.124,95%CI=1.254~29.907)、患侧淋巴结水肿(β=2.676,OR=14.521,95%CI=2.346~89.880)是乳腺癌患者康复期体力恢复不足的危险因素(P<0.05)。结论年龄、BMI、TNM分期、化疗、癌因性疲劳、患侧淋巴结水肿均能对乳腺癌患者康复期的体力恢复状况造成一定影响。

Objective To study the influence factors of insufficient physical recovery in breast cancer patients during rehabilitation.Methods From January 2016 to December 2018,116 patients who received regular follow-up after breast cancer surgery in Songzi Hospital of Traditional Chinese Medicine in Jingzhou City,Hubei Province were selected as the research objects.All patients were assessed by international physical activity questionnaire short form(IPAQ-SF).According to the results,all patients were divided into insufficient group(26 cases)and good group(90 cases).The clinical characteristics of the two groups were compared,and multivariate analysis was performed.Results There were 26 cases(22.41%)of patients with insufficient physical activity,63 cases(54.31%)were moderate,and 27 cases(23.28%)were active.There were statistically significant differences in the three types of patients in sitting time,activity time,overall physical activity consumption,and medium-to-high intensity activity days(P<0.05).Univariate analysis showed that there were statistically significant differences in the proportion of patients with age≥50 years old,body mass index(BMI)≥24 kg/m2,TNM stageⅢ-Ⅳ,chemotherapy,cancer-related fatigue and ipsilateral lymph node edema between the two groups(P<0.05).Multivariate analysis showed that age≥50 years(β=1.915,OR=6.789,95%CI=1.131-40.752),BMI≥24 kg/m2(β=2.420,OR=11.246,95%CI=1.889-66.952),TNM stageⅢ-Ⅳ(β=2.504,OR=12.234,95%CI=2.379-62.913),chemotherapy(β=1.736,OR=5.674,95%CI=1.324-24.316),cancer-related fatigue(β=1.812,OR=6.124,95%CI=1.254-29.907),lymph node edema on the affected side(β=2.676,OR=14.521,95%CI=2.346-89.880)were risk factors for insufficient physical recovery in convalescence of breast cancer patients(P<0.05).Conclusion Age,BMI,TNM stage,chemotherapy,cancer-related fatigue,and lymphedema on the affected side can all affect the physical recovery of breast cancer patients.