富血小板血浆治疗狭窄性腱鞘炎的临床研究

Clinical study of platelet rich plasma in the treatment of flexor tendon stenosing tenosynovitis

目的探讨富血小板血浆(platelet rich plasma,PRP)治疗屈指肌腱狭窄性腱鞘炎的临床疗效。方法选取2017年1月至2019年12月我院诊治的65例屈指肌腱狭窄性腱鞘炎患者,采用随机数字表法随机分成观察组32例,对照组33例。观察组行PRP注射治疗,对照组行曲安奈德注射治疗。分析两组患者治疗前与治疗后第2、4、8周手指关节活动度及视觉模拟疼痛评分(VAS)、治疗前后Quinnell评分、治疗总有效率、并发症发生情况。结果两组治疗前与治疗后第2周视觉模拟疼痛评分(VAS)及手指关节活动度、治疗前Quinnell评分、治疗后并发症发生率比较,差异无统计学意义(P>0.05);两组治疗后第4周与第8周视觉模拟疼痛评分(VAS)及手指关节活动度、治疗后Quinnell评分、治疗总有效率比较,差异有统计学意义(P<0.05)。结论富血小板血浆(PRP)治疗屈指肌腱狭窄性腱鞘炎疗效显著,可有效缓解临床症状,缩短疾病病程,无并发症风险,是一种值得推广的治疗方式。

Objective To explore the clinical effect of platelet rich plasma(Platelet rich plasma PRP)for the treatment of flexor tendon stenosing tenosynovitis.Methods From January 2017 to December 2019,65 patients with flexor tendon stenosing tenosynovitis were diagnosed and treated at our hospital using the random number table method,and were randomly divided into 32 cases in observation group and 33 cases in control group.The observa⁃tion group received PRP injections,while the control group received triamcinolone acetonide injections.Before and after treatment,finger range of motion and visual analogue pain score(VAS),Quinnell score,total effective rate of treatment,and complications were assessed.Results There was no statistically significant difference in VAS,Quinnell,or complications between the two groups before and after treatment(P>0.05).At 4 and 8 weeks after treatment,the VAS,range of motion of finger joints,Quinnell score after treatment,and total effective rate were compared between the two groups,and the differences were statistically significant(P<0.05).Conclusion Platelet rich plasma(PRP)is an effective treatment for flexor tendon stenosing tenosynovitis,which can effectively alleviate the clinical symptoms,shorten the course of disease,and has no risk of complications.It is a treatment that should be promoted.