miR169在植物生长发育与非生物胁迫响应中的作用

The Role of miR169 Family Members in the Processes of Growth,Development and Abiotic Stress Response in Planta

MicroRNA(miRNA)是一类由内源基因编码的、长度为18~36 bp的小非编码单链RNA分子,通过序列互补降解或抑制其靶标基因转录后的翻译过程,对植物的器官形成、生长发育、维持基因组完整性以及非生物胁迫应答等方面起重要作用。miRNA169家族是植物中广泛存在且较为保守的microRNA家族,调控植物中一类保守的转录因子NF-YA(Nuclear transcription factor Y subunit A),miR169/NF-Y可能在植物的根系发育、侧生器官形成、花器官形成、气孔形成及胁迫应答方面具有重要作用。然而目前对于miRNA169的研究主要集中在植物的生长发育调控方面,其参与应答非生物胁迫调控网络方面报道较少。本文从miRNA169家族的起源进化机制和参与植物的生长发育过程及高盐、干旱、低温及重金属等非生物胁迫响应等方面展开论述,同时对其他生物胁迫进行概述,以期为miRNA169家族的发展概况及响应相关胁迫的研究提供参考。

MicroRNA(miRNA)is a well-studied small non-coding single-stranded RNA molecules encoded by endogenous genes with a length of about 18-36 bp.It plays a key role in plant organ formation,growth and development,maintenance of genomic integrity and responses to abiotic stress.Among them,the miRNA169 family is detected widely with levels of conservativation in plants,and these family members participat into the regulation of a kind of conserved transcription factor NF-YA at post-transcriptional level.They are known crucial role in root development,lateral organ formation,floral organ formation,stomatal formation and stress of plants.Here we reviewed the origin and evolutionary mechanism of the miRNA169 family and its involvement in plant growth and response to abiotic stresses(high salinity,drought,low temperature and heavy metals)as other stresses conditions.We wish to provide insight of future understanding the biological function of miRNA169 family members responding to various stresses.