台州地区不同年龄人群的维生素D营养现况调查

Investigation on the status quo of vitamin D nutrition of people in different ages in Taizhou area

目的了解台州地区不同年龄人群中维生素D的营养现况,寻找维生素D缺乏的主要人群,为后续防治维生素D缺乏提供必要的科学依据。方法回顾性分析2017年8月至2019年12月送检于台州恩泽医疗中心(集团)恩泽医院的应用高效液相色谱串联质谱法检测维生素D的17815例血清标本,按年龄分为7组,分别是新生儿、婴儿、儿童、少年、青年、中年和老年组。结果检测总人群的维生素D水平为23.31(17.98~29.59)ng/mL。维生素D水平在新生儿组、婴儿组、儿童组、少年组、青年组、中年组和老年组分别为17.39(14.21~29.91)ng/mL、35.08(29.71~41.41)ng/mL、26.41(21.91~31.45)ng/mL、20.61(16.81~24.43)ng/mL、21.59(16.22~28.71)ng/mL、22.61(17.77~27.45)ng/mL和22.12(16.98~27.81)ng/mL。各年龄组间差异有统计学意义(P<0.01)。在维生素D营养状况评估中,维生素D缺乏占6.16%、不足占27.96%、正常占65.88%,以维生素D血清含量正常为主。各年龄组间以新生儿组最为缺乏,青少年组其次,再次之是中老年组。各年龄组间维生素D营养状况差异有统计学意义(P<0.05)。结论台州地区就诊人群中维生素D水平以正常为主,但除婴儿组外其余不同年龄段均存在不同程度的维生素D缺乏,尤其以新生儿和青少年最为缺乏。

Objective To understand the status quo of vitamin D nutrition of people in different ages in Taizhou area,and to find out the main people with vitamin D poverty,so as to provide necessary scientific basis for the follow-up prevention and treatment of vitamin D poverty.Methods A total of 17815 cases of serum samples of vitamin D detected by high performance liquid chromatography combined with tandem mass spectrometry sent to and examined in Enze Hospital of Taizhou Enze Medical Center(Group)from August 2017 to December 2019 were analyzed retrospectively.They were divided into the neonate group,the infant group,the child group,the teenager group,the youth group,the middle-aged group and the elderly group according to their ages.Results The vitamin D level of the total population was 23.31(17.98-29.59)ng/mL.The levels of vitamin D in the neonate group,the infant group,the child group,the teenager group,the youth group,the middle-aged group and the elderly group were 17.39(14.21-29.91)ng/mL,35.08(29.71-41.41)ng/mL,26.41(21.91-31.45)ng/mL,20.61(16.81-24.43)ng/mL,21.59(16.22-28.71)ng/mL,22.61(17.77-27.45)ng/mL and 22.12(16.98-27.81)ng/mL,respectively,with statistically significant differences in different age groups(P<0.01).In the assessment of status of vitamin D nutrition,vitamin D poverty accounted for 6.16%,deficiency accounted for 27.96%,and normal accounted for 65.88%,mainly with the normal serum content of vitamin D.In all age groups,the neonate group was the most poverty,the youth group and the teenager group were the second,and the middle-aged group and the elderly group were the third.There were statistically significant differences in status of vitamin D nutrition in different age groups(P<0.05).Conclusion The vitamin D level in patients of Taizhou area is mainly normal,but vitamin D poverty with different degrees exists in different age groups except for the infant group,especially in the neonate group,the youth group and the teenager group.