Glaucoma-like damage induced by S100B injection is accompanied by microglial response

Glaucoma is currently the second leading cause of blindness worldwide.Due to aging societies the number of patients suffering from this disease will further increase in the next years.Unfortunately,glaucoma can remain asymptomatic until it is rather far progressed,hence about 10–50% of patients are unaware they suffer from this disease.Glaucoma is a progressive optic neuropathy associated with changes at the optic nerve head.