仙方活命饮在溃疡性结肠炎中的应用研究进展

Research progress of Xianfang Huoming Decoction in the treatment of ulcerative colitis

溃疡性结肠炎的发病机制尚不十分明确,为主要累及直肠、结肠黏膜的炎症性疾病,病情反复,缠绵难愈。近年来中药内服在治疗溃疡性结肠炎的近、远期临床效果,改善患者生活质量等方面被广大医患所认可。很多临床研究显示仙方活命饮复方治疗溃疡性结肠炎临床效果明确。本文将仙方活命饮的处方功效、组方分析及所含药物的药理作用等方面与溃疡性结肠炎的发病原因和治疗上的作用机制相关联,讨论仙方活命饮治疗溃疡性结肠炎的理论依据,为其更好地应用于溃疡性结肠炎的治疗提供思路。

The pathogenesis of ulcerative colitis is not yet clear.It is an inflammatory disease mainly involving the rectum and the colonic mucosa.The disease is repeated and difficult to cure.In recent years,the internal administration of traditional Chinese medicine has been recognized by the majority of doctors and patients in terms of the short-term and long-term clinical effects in the treatment of ulcerative colitis and the improvement of patients’quality of life.Many clinical studies have shown that Xianfang Huoming Decoction in compound has a clear clinical effect on the treatment of ulcerative colitis.This article discusses the theoretical basis for the treatment of ulcerative colitis by comparing the prescription efficacy,formulation analysis and pharmacological action of the drugs contained with the pathogenesis and therapeutic mechanism of ulcerative colitis,and provides ideas for its better application in the treatment of ulcerative colitis.