表面增强拉曼散射技术在蛋白质类物质检测中的研究进展

Progress of Surface Enhanced Raman Scattering and Application for Proteins Analysis

许多与食品成分及疾病相关的生物标记物均含有蛋白质,因而在食品、医学、药学等领域对蛋白质类物质的检测提出新要求。介绍表面增强拉曼散射(SERS)的发展及在蛋白质类物质检测中的研究情况,综述基于SERS的直接检测法和其他联用技术,对其在蛋白质类物质检测中的应用进行总结和展望,为基于SERS的蛋白质类物质检测技术的发展提供参考。

Proteins exists in many food ingredients and disease-related biomarkers.Therefore,the new requirements for the detection of protein in the fields of medicine,pharmacy and food were much in demand.The development of surface enhanced Raman scattering SERS and its application for protein analysis were introduced.The direct detection method of SERS and SERS-coupled with other techniques was reviewed.The application of SERS in protein detections was summarized and prospected.