2004—2017年广州市女性乳腺癌发病趋势分析

Trend of Incidence of Female Breast Cancer in Guangzhou City from 2004 to 2017

[目的]分析2004—2017年广州市女性乳腺癌发病特征及趋势。[方法]根据广州市肿瘤登记处收集的2004年1月至2017年12月女性乳腺癌发病病例资料,计算广州市女性乳腺癌粗发病率、年龄别发病率、中国人口标化率(中标率)、世界人口标化率(世标率)、平均年度变化百分比(AAPC)。[结果] 2004—2017年广州市共报告女性乳腺癌病例28 873例,粗发病率为51.93/10万,中标率为39.97/10万,世标率为37.33/10万,城区、郊区和郊县世标率分别为48.96/10万、29.45/10万和17.54/10万,AAPC (95%CI)分别为-0.79%(-1.50%~-0.10%)、2.94%(2.00%~3.80%)和9.69%(8.10%~11.30%),城区发病呈现下降趋势,郊区及郊县发病呈现上升趋势;三地区女性乳腺癌发病均于45~59岁年龄段达到高峰水平。[结论]广州市女性乳腺癌发病率较高,应加强45岁以上,尤其是郊区、郊县女性人群的筛查和宣教工作。

[Purpose] To analyze the trend of incidence of female breast cancer in Guangzhou City from 2004 to 2017.[Methods] Data of female breast cancer from January 2004 to December 2017 were collected from Guangzhou Cancer Registry. The crude incidence, age-standardized incidence rate of Chinese standard population in 2000(ASR-C) and of world population(ASR-W), annual average change percentage(AAPC) of female breast cancer in Guangzhou City were calculated.[Results] A total of 28 873 female breast cancer cases reported in Guangzhou City from 2004 to 2017, the crude incidence rate was 51.93/105, ASR-C was 39.97/105 and ASR-W was 37.33/105. ASR-W of urban areas, suburban areas and county areas was 48.96/105, 29.45/105 and 17.54/105, respectively;AAPC(95%CI) was-0.79%(-1.50%~-0.10%), 2.94%(2.00%~3.80%) and 9.69%(8.10%~11.30%),respectively. The incidence of female breast cancer in urban areas showed a downward trend,while the incidence in suburban areas and county areas showed an upward trend. The incidence of female breast cancer reached a peak at age group of 45~59. [Conclusion] There is a high incidence of female breast cancer in Guangzhou City, screening and prevention promotion should be strengthened for women over 45 years old, especially in suburban areas and county areas.