血府逐瘀汤加减治疗原发性痛经气滞血瘀型的临床观察

Clinical observation of Xuefu Zhuyu Decoction in the treatment of primary dysmenorrhea with Qi stagnation and blood stasis

目的分析妇科原发性痛经(气滞血瘀型)患者治疗需求,评价中药血府逐瘀汤加减治疗的安全性及有效性。方法96例妇科原发性痛经患者为研究对象,依据治疗方法不同分为西药组与中药组,各48例。西药组予以双氯芬酸钠缓释片治疗,中药组予以血府逐瘀汤治疗。对比两组临床疗效、不良反应发生情况、疼痛程度、中医症候总积分情况。结果中药组总有效率为95.83%高于西药组的83.33%,差异具有统计学意义(P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。治疗3个月后,中药组视觉模拟评分法(VAS)评分及中医症候总积分分别为(0.60±0.20)、(7.50±0.50)分,均低于西药组的(1.05±0.30)、(11.50±1.20)分,差异均具有统计学意义(P<0.05)。结论比较西药治疗,中药血府逐瘀汤加减治疗原发性痛经可有效促进患者症状体征改善,具有安全性、有效性优势。

Objective To analyze the treatment needs of patients with primary dysmenorrhea(Qi stagnation and blood stasis type),and to evaluate the safety and effectiveness of traditional Chinese medicine of Xuefu Zhuyu Decoction.Methods A total of 96 patients with primary dysmenorrhea as study subjects were divided into Western medicine group and traditional Chinese medicine group according to different treatment methods,with 48 cases in each group.Western medicine group was treated with diclofenac sodium sustainedrelease tablets,and traditional Chinese medicine group was treated with Xuefu Zhuyu Decoction.The clinical efficacy,occurrence of adverse reactions,pain degree,and total score of traditional Chinese medicine syndromes were compared between the two groups.Results The total effective rate 95.83%of traditional Chinese medicine group was higher than 83.33%of Western medicine group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in incidence of adverse reactions between the two groups(P>0.05).3 months after treatment,the visual analogue scale(VAS)score(0.60±0.20)points and total score of traditional Chinese medicine(7.50±0.50)points of traditional Chinese medicine group were lower than(1.05±0.30)and(11.50±1.20)points of Western medicine group,and the difference was statistically significant(P<0.05).Conclusion Compared with the treatment of Western medicine,the traditional Chinese medicine of Xuefu Zhuyu Decoction can improve the symptoms and signs of patients with primary dysmenorrhea,and has the advantages of safety and effectiveness.