微反应器中合成二甲基二烯丙基氯化铵的研究

Research on synthesis of dimethyldiallylammonium chloride in a microreactor

利用微反应器设计了连续合成二甲基二烯丙基氯化铵的新工艺,考察了反应温度、物料摩尔比、停留时间对反应的影响,并通过单因素条件对实验工艺进行优化。结果表明,较优的实验条件为:n(二甲胺)∶n(氢氧化钠)∶n(氯丙烯)=1∶1∶2.1、反应温度为45℃、停留时间为11 min,此时产品收率为92%。与传统间歇"一步法"工艺相比,该微反应工艺简化了操作,缩短了反应时间,并且提高了收率。

A novel continuous synthesis process for dimethyldiallylammonium chloride in a microreactor is designed.The influences of reaction temperature,molar ratio of raw materials and residence time on the reaction are observed,and the process is modified from single-factor conditional experiment.It is found that the product yield reaches 92% under the optimized conditions that n( dimethylamine) ∶n( sodium hydroxide) ∶n( allyl chloride) = 1 ∶1 ∶2. 1,reaction temperature is45℃ and residence time is 11 min. Compared with traditional one-step process,the microreactor process can simplify procedures,shorten reaction time,and realize higher yield.