胃溃疡癌变合并真菌感染患者应用腹腔镜胃穿孔修补术治疗的临床效果探究

Clinical Effect of Laparoscopic Gastric Perforation in Patients With Gastric Ulcer Cancer and Fungal Infection

目的探讨腹腔镜胃穿孔修补术对胃溃疡(GU)癌变合并真菌感染患者的疗效及安全性。方法选择90例GU癌变合并真菌感染患者,随机数表法分为观察组和对照组,各45例。对照组采用胃癌根治术,观察组采用腹腔镜胃穿孔修补术。比较两组的疗效、临床治疗相关指标以及术后并发症的发生率。结果观察组的临床总有效率为93.33%,较对照组的77.78%显著高(P<0.05);观察组的手术时间、术中出血量、术后肛门排气时间、肠鸣音恢复时间、住院时间、术后1w真菌检出率、疼痛视觉模拟评分(VAS)均显著低于对照组(P<0.05);观察组术后并发症的发生率为4.44%,较对照组的31.11%显著低,差异具有统计学意义(P<0.05)。结论 GU癌变合并真菌感染患者应用腹腔镜胃穿孔修补术可减少术中出血量,缩短手术时间、肛门排气时间、肠鸣音恢复时间及住院时间,减轻疼痛,疗效显著且安全性高,值得临床推广。

Objective To investigate the efficacy and safety of laparoscopic gastric perforation repair in patients with gastric ulcer(GU)cancer and fungal infection.Methods A total of 90 patients with GU and fungal infections were selected.The random number table method was used to divide them into observation group and control group,each with 45 cases.The control group received radical gastrectomy and the observation group received laparoscopic repair of gastric perforation.Compare the efficacy,clinical treatment-related indicators and the incidence of postoperative complications in the two groups.Results The total clinical effective rate of the observation group was 93.33%,which was significantly higher than 77.78% of the control group(P<0.05).The operation time,intraoperative blood loss,postoperative anal exhaust time,bowel sound recovery time,hospitalization time,1 w postoperative fungal detection rate,and VAS of the observation group were significantly lower than those of the control group(P<0.05).The incidence of postoperative complications in the observation group was 4.44%,which was significantly lower than that in the control group(31.11%).The difference was statistically significant(P<0.05).Conclusion Laparoscopic gastric perforation repair for patients with GU cancer and fungal infection can reduce intraoperative blood loss,shorten operation time,anal exhaust time,bowel sound recovery time and hospitalization time,reduce pain,and have significant effect and high safety,which is worthy of clinical promotion.