宫颈癌病理分期与临床分期差异性及影响淋巴结转移的危险因素分析

Analysis of the Difference Between Pathological Stage and Clinical Stage of Cervical Cancer and the Risk Factors Influencing Lymph Node Metastasis

目的探究宫颈癌病理分期与临床分期差异性及影响淋巴结转移的危险因素,以此为临床提供科学的理论作为参考。方法纳入80例宫颈癌患者临床资料进行回顾性分析,针对患者的病理分期和临床分期进行分析,并予以比较,同时了解淋巴结转移的危险因素。结果临床分期ⅠA、ⅠB、ⅡA、ⅡB期符合率分别为66.67%、62.50%、57.14%、53.33%,临床分期总符合率为60.00%。单因素分析显示,有/无淋巴结转移在临床分期、有无化疗、肌层浸润深度、宫旁组织浸润、肿瘤直径各因素方面差异有统计学意义(P<0.05)。Logistic多因素分析显示,高临床分期、有化疗、肌层浸润深度>1/2肌层、有宫旁组织浸润、肿瘤直径≥4cm是影响淋巴结转移的独立危险因素(P<0.01)。结论在宫颈癌的分期中,临床分期相较于病理分期符合率偏低,临床分期、是否化疗、肌层浸润深度、宫旁组织浸润、肿瘤直径等是淋巴结转移的危险因素。

Objective To explore the difference between pathological and clinical stages of cervical cancer and the risk factors affecting lymph node metastasis,so as to provide scientific theories for clinical reference.Methods The clinical data of 80 patients with cervical cancer were retrospectively analyzed.The pathological stage and clinical stage of the patients were analyzed and compared,and the risk factors of lymph node metastasis were also understood.Results The clinical staging Ⅰ,Ⅰ B,A and B ⅡⅡ coincidence rate was 66.67%(8/12),62.50%(20/32),57.14%(12/21),53.33%(8/15),clinical staging total coincidence rate was60.00%(48/80).Univariate analysis showed that there were statistically significant differences in clinical stage,chemotherapy,depth of muscular layer infiltration,periuterine tissue infiltration,and tumor diameter with or without lymph node metastasis(P<0.05).Logistic multivariate analysis showed that high clinical stage,chemotherapy,muscular layer infiltration depth>1/2 muscular layer,periuterine tissue infiltration,and tumor diameter ≥4 cm were independent risk factors for lymph node metastasis(P<0.01).Conclusion In the stage of cervical cancer,the coincidence rate of clinical stage is lower than that of pathological stage.Clinical stage,chemotherapy,depth of muscle layer infiltration,invasion of parietal tissue and tumor diameter are risk factors for lymph node metastasis.