浅表肢端纤维黏液瘤1例

A Case of Superficial Acral Fibromyxoma

患者男,24岁,左手中指指腹肤色结节3年。皮肤科情况:左手中指第二指腹侧可见一0.7 cm×0.6 cm大小肤色结节,质硬,表面光滑,边界清楚,表面无破溃、糜烂。皮损组织病理示:表皮大致正常,真皮内及皮下组织内可见一界限清楚、无包膜的肿瘤。肿瘤由束状、编织状排列的短梭形、卵圆形和星形肿瘤细胞组成,其间有较多分支状的小到中等的薄壁血管。肿瘤组织内可见大量黏液样物质沉积,散在肥大细胞。肿瘤细胞无明显异型性。免疫组织化学:CD34(弥漫+)、CD68(灶状+),S-100(-),Ki-67(2%+)。诊断:浅表肢端纤维黏液瘤。

A 24-year-old male presented with a nodule arising on the ventral of his left middle finger for 3 years.Physical examination showed a skin color nodule with smooth surface and well-defined margins,which measured approximately 0.7 cm×0.6 cm.There was no rupture or erosion.Histopathological examination revealed proliferation of spindled and stellate-shaped monomorphous cells,arranged in a random,loose fascicular or storiform growth pattern,within a myxoid collagenous stroma and a prominent microvasculature.The Immunohistochemical study revealed of the neoplastic cells positive for CD34 and CD68 and negative for S100.The diagnosed of superficial acral fibromyxoma was made.