有关急性链球菌感染后肾小球肾炎病情迁延高危因素的研究进展

Risk Factors for Prolonged Glomerulonephritis after Acute Post-streptococcal Glomerulonephritis

急性链球菌感染后肾小球肾炎(APSGN)大多数患儿的预后较好,但是仍有一部分患儿的病情迁延不愈,进一步发展为慢性肾脏病,甚至进入终末期肾病阶段。近年来,在患儿急性链球菌感染后肾小球肾炎方面有了重要进步,本研究通过APSGN的临床特征、诊断、易主易感因素、发病机制、病情迁延的高危因素及其相关性分析等方面最新进展进行综述。

The prognosis of most children with acute post-streptococcal glomerulonephritis(APSGN)is good,but there are still some children who persist in the disease and further develop into chronic kidney disease or even enter the stage of end-stage renal disease.In recent years,important progress has been made in the treatment of glomerulonephritis after acute streptococcal infection in children.this study is to review the latest progress in the clinical features,diagnosis,predisposing factors,pathogenesis,high risk factors for persistent disease and correlation analysis of APSGN.