2009~2015年甘肃省肿瘤登记地区胃癌流行特征及变化趋势分析

Epidemiological Characteristics and Trend in Gastric Cancer in Cancer Registration Areas in Gansu Province,2009~2015

目的:分析2009~2015年甘肃省肿瘤登记地区的胃癌发病与死亡情况,为胃癌防控提供依据。方法:按照全国肿瘤登记中心制定的审核方法和标准,收集甘肃省肿瘤登记地区上报的2009~2015年胃癌发病和死亡数据,按地区、性别、年龄进行分层,计算胃癌发病与死亡的粗率、中国人口标化率(中标率)、世界人口标化率(世标率)、累积率、截缩率、构成比、顺位及年百分比改变(annual percentage change,APC),并描述2009~2015年胃癌的发病(死亡)变化趋势。结果:2009~2015年甘肃省肿瘤登记地区收集胃癌新发病例20088例。发病率53.04/10万(男性77.58/10万,女性27.15/10万),中标发病率为49.00/10万,世标发病率55.60/10万,居全省恶性肿瘤发病顺位第1位,占所有恶性肿瘤新发病例的23.12%;胃癌死亡病例8495例,死亡率为41.74/10万(男性60.20/10万,女性21.98/10万),中标死亡率为40.88/10万,世标死亡率48.72/10万,居全省恶性肿瘤死亡顺位第1位,占所有癌症死亡病例的31.04%;胃癌发病率和死亡率皆随年龄增长而上升,城市高于农村,男性高于女性的特点;甘肃省2009~2015年胃癌发病率和死亡率分别呈现平稳和下降趋势。胃癌发病率分性别、地区下降趋势均不明显,无统计学意义(P>0.05);胃癌死亡率下降趋势明显,有统计学意义(P<0.05)。结论:甘肃省胃癌发病率和死亡率均居全省恶性肿瘤首位,对居民身心健康造成严重危害,应在高发区开展胃癌的高危人群评估和早诊早治筛查,以期有效降低胃癌发病率和死亡率。

Objective:To analyze the incidence andmortality of gastric cancer in cancer registration areas in GansuProvince from 2009 to 2015,so as to provide evidence for theprevention and control of gastric cancer.Methods:According to the audit methods and standards established by the National Cancer Registration Center,we collected data of gastric cancer from 2009 to 2015 by area,gender and age from cancer registries in Gansu Province.The crude rates of incidence and mortality,cumulative incidence/mortality rates,truncated incidence/mortality rates,proportions and rankings of cancer were calculated.Chinese standard population in 2000 and the Segi(world)population were applied for calculating age-standardized incidence/mortality rates.Annual percentage change(APC)was used to evaluate the trend of gastric cancer incidence and mortality.Results:The number of new cases of gastric cancer were 20,088 in cancer registration areas in Gansu Province from 2009 to 2015.The incidence rate was 53.04/10^(5)(77.58/10^(5) in the male,27.15/10^(5) in the female);the age-standardized incidence rates by Chinese standard population(ASIRC)and by world standard population(ASIRW)were 49.00/10^(5) and 55.60/10^(5),ranking first in the cancer incidence ranking,and accounting for 23.12%of new cases of all malignant tumors.During the same period,there were 8,495 death cases of gastric cancer in cancer registration areas in Gansu Province from 2009 to 2015.The mortality rate was 41.74/10^(5)(60.20/10^(5) in the male,21.98/10^(5) in the female);the age-standardized mortality rates by Chinese standard population(ASMRC)and by world standard population(ASM RW)were 40.88/10^(5) and 48.72/10^(5),ranking first in the cancer mortality ranking.Both incidence and mortality of gastric cancer increased with the growth of age;both data were higher in urban than rural areas;and higher in males than females.Both incidence and mortality of gastric cancer in Gansu Province steadily decreased from 2009 to 2015.The mortality rate of gastric cancer by gender and region declined significantly(P<0.05),while the incidence of it did not declined significantly(P>0.05).Conclusion:From 2009 to 2015,both incidence and mortality of gastric cancer rank first among all malignancy in Gansu Province,which seriously threaten people’s physical and mental health.Assessment and screenings for early diagnosis and treatment of gastric cancer should be carried out in high-incidence areas,in order to effectively reduce the incidence and mortality of gastric cancer.