2016年河南省宫颈癌发病与死亡状况分析

Incidence and Mortality of Cervical Cancer in Henan Province,2016

目的:根据河南省肿瘤登记地区肿瘤登记数据估算河南省2016年宫颈癌发病和死亡流行特征,为河南省的宫颈癌防治研究提供基础数据。方法:按照《中国肿瘤登记手册》以及国际癌症研究中心的肿瘤登记数据质量标准评估2016年河南省肿瘤登记数据的完整性、有效性和可靠性。按照ICD-10编码(C53)提取宫颈癌数据,并分别计算城镇及农村、不同年龄组登记人群的宫颈癌发病率和死亡率。结合2016年全省人口数据估算全省宫颈癌的发病例数和死亡例数,计算全省宫颈癌发病率及死亡率、构成比、0~74岁累积率和标准化率。结果:2016年河南省宫颈癌新发病例数为10948例,发病率为21.09/10万,中标发病率为16.99/10万,世标发病率为15.88/10万;死亡病例数为3666例,死亡率为7.06/10万,中标死亡率为5.18/10万,世标死亡率为4.97/10万。农村地区的宫颈癌中标发病率、世标发病率和中标死亡率、世标死亡率均高于城市地区。宫颈癌年龄别发病率在35岁之前低于10.00/10万,50~岁年龄组达到峰值;宫颈癌的年龄别死亡率在45岁之前低于10.00/10万,80~岁年龄组达到峰值。结论:河南省宫颈癌疾病负担严重,防控形势严峻,应加强宫颈癌的一级预防和二级预防,减轻宫颈癌的健康危害。

Objective:To estimate the incidence and mortality of cervical cancer in Henan Province in 2016 based on registered cancer data,and provide basic data for the prevention and treatment of cervical cancer in Henan Province.Methods:Integrity,validity and reliability of data in 2016 from local registries were assessed according to criteria of Guideline on Cancer Registration in China,International Agency for Research on Cancer(IARC)and International Association of Cancer Registries(IACR).Cervical cancer data(ICD-10-CM Diagnosis Code C53)were extracted from databases,and incidences and mortality by gender,age and areas(urban vs rural)were calculated.With demographic data in 2016,we estimated incidence and mortality,cumulative rates(0〜74 years old)and age-standardized rates by China(2000)and world(Segi)standard population of cervical cancer in Henan Province.Results:There were 10,948 cases of cervical cancer in Henan in 2016;the crude incidence rate was 21.09/100,000;the age-standardized incidence rates by Chinese standard population(ASIRC)and by world standard population(ASIRW)were 16.99/100,000 and 15.88/100,000,respectively.3,666 cervical cancer cases dead in 2016;the crude mortality rate was 7.06/100,000,the age-standardized mortality rates by Chinese standard population(ASMRC)and by world standard population(ASMRW)were 5.18/100,000 and 4.97/100,000,respectively.At the same time,ASIRC and ASMRC of cervical cancer were higher in rural areas than in urban areas in Henan Province.The age-specific incidence rate of cervical cancer was lower than 10.00/100,000 in the<35 age group,and peaked in the 50〜age group.The age-specific mortality rate of cervical cancer was lower than 10.00/100,000 in the<35 age group,and peaked in the 80~age group.Conclusion:Cervical cancer in Henan Province was prevalent,and the prevention and control of it was severe.Primary and secondary prevention of cervical cancer should be strengthened to reduce the risks of cervical cancer.