期刊文献+

低分子肝素辅助治疗AECOPD并肺心病患者的效果及对患者心功能和凝血功能的影响 被引量:4

Effect and Safety of Low Molecular Weight Heparin in Adjuvant Treatment of AECOPD Patients with Pulmonary Heart Disease and Influence on Cardiac Function and Coagulation Function of Patients
下载PDF
导出
摘要 目的:探究低分子肝素钙(LMWHC)治疗慢性阻塞性肺疾病急性加重期(AECOPD)并肺心病患者的效果。方法:选取2017年8月-2019年8月于笔者所在医院就诊的AECOPD合并肺心病的患者94例,按照随机数字表法分为对照组和研究组,各47例。对照组予以常规治疗,研究组在对照组的基础上联合LMWHC治疗,观察两组患者临床疗效、心功能及凝血功能。结果:研究组总有效率(95.74%)明显高于对照组(80.85%),差异有统计学意义(P<0.05)。治疗后,研究组EDV、ESV水平和D-D水平明显低于对照组(P<0.05),RVEF水平和PT、APTT水平明显高于对照组(P<0.05)。结论:低分子肝素钙治疗AECOPD并肺心病的临床效果显著,可有效改善患者心功能和凝血功能情况。 Objective:To explore the effect of Low Molecular Weight Heparin Calcium(LMWHC)in the treatment of patients with acute exacerbation chronic obstructive pulmonary disease(AECOPD)and pulmonary heart disease.Method:A total of 94 patients with AECOPD and pulmonary heart disease in our hospital from August 2017 to August 2019 were selected and divided into control group and study group by random table method,47 cases in each group.The control group was given conventional treatment,and the study group was treated with LMWHC on the basis of the control group.The clinical efficacy,cardiac function and coagulation function of the two groups were observed.Result:The total effective rate of the study group(95.74%)was significantly higher than 80.85%of the control group,the difference was statistically significant(P<0.05).After treatment,the levels of EDV,ESV and D-D in the study group were significantly lower than those in the control group(P<0.05),and the levels of RVEF,PT and APTT in the study group were significantly higher than those in the control group(P<0.05).Conclusion:The clinical effect of Low Molecular Weight Heparin Calcium in the treatment of AECOPD with pulmonary heart disease is significant,which can effectively improve the cardiac function and coagulation function of patients.
作者 袁桂林 YUAN Guilin(People’s Hospital of Yubei District in Chongqing,Chongqing 401120,China)
出处 《中外医学研究》 2021年第21期48-50,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 低分子肝素钙 慢性阻塞性肺疾病 肺心病 凝血功能 Low Molecular Weight Heparin Calcium Chronic obstructive pulmonary disease Pulmonary heart disease Coagulation function
  • 相关文献

参考文献10

二级参考文献97

  • 1慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量:8233
  • 2Tavazzi L,Tognoni G,Franzosi MG. Rationale and design of the GISSI heart failure trial:a large trial to assess the effects of n-3 polyunsaturated fatty acids and rosuvastatin in symptomatic congestive heart failure[J].{H}European Journal of heart failure,2004,(05):635-641.
  • 3KaradagF,KirdarS,Karul AB. The value of C-reactive protein as a marker of systemic inflammation in stable chronic obstructive pulmonary disease[J].{H}European Journal of internal medicine,2008,(02):104-108.
  • 4Rhodes CJ,DavidsonA,Gibbs JS. Therapeutic targets in pulmonary arterial hypertension[J].{H}Pharmacology & Therapeutics,2009,(01):69-88.
  • 5Ridker PM,Danielson E,Fonseca FA. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein[J].{H}New England Journal of Medicine,2008,(21):2195.
  • 6瞿慧君.低分子肝素治疗慢性阻塞性肺疾病急性加重期并发肺源性心脏病的临床疗效观察[J].实用心脑肺血管病杂志,2015,23(7):121-123.
  • 7甘学军,汪小华,胡刚.低分子肝素钙皮下注射治疗慢性阻塞性肺疾病并肺心病急性加重期的临床疗效分析[J].实用心脑肺血管病杂志,2016,24(3):156-157.
  • 8李良,夏云峰,刘润梅,翟红霞,殷亚昕,张津津,陈海威.67例肺栓塞患者的回顾性研究[J].解放军医学杂志,2008,33(9):1132-1135. 被引量:15
  • 9李志波,林淑媚.低分子肝素钙治疗慢性阻塞性肺疾病急性加重期的临床观察[J].中国实用医药,2009,4(22):34-36. 被引量:8
  • 10李洁,边红,卢长林,郑华,王建旗.阿托伐他汀抑制C反应蛋白对肺动脉平滑肌细胞的促炎作用研究[J].中华老年心脑血管病杂志,2009,11(10):787-790. 被引量:4

共引文献92

同被引文献39

引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部