南阳市结核病防治机构就诊人员非结核分枝杆菌检出结果分析

Analysis on the detection results of non tuberculosis mycobacteria among the patients in tuberculosis prevention and control institutions in Nanyang City

目的分析南阳市结核病防治机构就诊人员非结核分枝杆菌(NTM)阳性检出率及分布范围,从而有助于医疗检测防治机构对非结核分枝杆菌病的防治、诊断水平,降低非结核分枝杆菌病对人类健康的损害。方法选取2019年—2020年6月本市结防机构就诊的改良罗氏痰培养抗酸杆菌阳性的患者1788例,进行对硝基苯甲酸生长试验(PNB),PNB阳性菌株即为非结核分枝杆菌复合群,经筛查有193例确定为非结核分枝杆菌。结果南阳市结防机构就诊的患者非结核分枝杆菌总检出率各县分布很不均衡,为5.31%~17.61%,平均为10.79%,仍处于较高水平。经鉴定胞内分枝杆菌占91.19%。结论在做好可疑结核病症状者的痰抗酸菌涂片检查的同时,应扩大非结核分枝杆菌检测工作,以及时发现非结核分枝杆菌肺病,落实有效的治疗管理,做针对性的治疗。

Objective To analyze the positive detection rate and distribution range of non tuberculous Mycobacterium(NTM)in patients of tuberculosis prevention and control institutions in Nanyang City,so as to contribute to the prevention and diagnosis level of non tuberculous Mycobacterium disease in medical detection and control institutions,and reduce the damage of non tuberculous Mycobacterium disease to human health.Methods A total of 1788 patients with positive acid fast bacilli from modified Roche sputum culture in our city from 2019 to June 2020 were selected for PNB growth test.The positive strains of PNB were nontuberculous mycobacteria complex group,and 193 cases were identified as nontuberculous mycobacteria after screening.Results The total detection rate of nontuberculous Mycobacteria in Nanyang City was uneven,ranging from 5.31%to 17.61%,with an average of 10.79%.After identification,91.19%of the patients had intracellular mycobacteria.Conclusion While doing a good job in sputum smear examination of acid fast bacteria in patients with suspected tuberculosis symptoms,we should expand the detection of non tuberculosis mycobacteria,timely discover non tuberculosis mycobacteria pulmonary disease,implement effective treatment management,and do targeted treatment.