植物环状RNA研究进展

Research Progress of Plant Circular RNA

环状RNA(circular RNA,circRNA)主要是真核细胞通过反向剪接作用使3′末端和5′末端共价结合而形成的一条单链非编码RNA分子,它是一种特殊的非编码RNA(noncoding RNA,ncRNA),在多种生物体中广泛存在。综述了植物中circRNA鉴定方法、分子特征以及潜在的生物学功能等方面,表明circRNA可能在生物胁迫、非生物胁迫以及生长和发育中发挥重要作用,并以动物中circRNA的研究进展为基础,对植物中circRNA的局限性和应用前景进行讨论。

Circular RNA(circRNAs)is mainly a single-stranded non-coding RNA molecule formed by covalent binding of 3′and 5′ends by reverse splicing of eukaryotic cells.It is a special non-coding RNA(non-coding RNA,ncRNA),which exists widely in many organisms.In this paper,the identification methods,molecular characteristics and potential biological functions of circRNA in plants were reviewed.It was indicated that circRNA may play an important role in biological stress,abiotic stress,growth and development.Based on the research progress of circRNA in animals,the limitations and application prospects of circRNA in plants were discussed.