针刺水沟穴治疗缺血性脑损伤机制研究进展

Research Progress on the Mechanism of Needling DU26 in Treating Cerebral Ischemia Injury

水沟穴作为治疗缺血性脑损伤的主穴,具有确定的疗效,目前研究其主要机制包括:抑制炎性因子表达、保护和调节血脑屏障、抑制细胞凋亡、促进血管新生、促进神经功能重塑、缩小梗死面积、调节脑血管舒缩功能和调节能量代谢等。

Shuigou acupoint(DU26)is the main acupoint for the treatment of cerebral ischemia with a positive curative effect.The mechanism of needling DU26 mainly included inhibiting inflammatory factors expressions,protecting and regulating the blood-brain barrier,inhibiting cell apoptosis,promoting angiogenesis,promoting the remodeling of nerve function,reducing the infarct area,regulating the vasomotor function of brain and regulating energy metabolism.