神经外科患者耐碳青霉烯类肺炎克雷伯菌肺部感染的影响因素与经济负担分析

Analysis of influencing factors and economic burden of carbapenem-resistant Klebsiella pneumoniae pulmonary infection in neurosurgical patients

目的分析某三甲医院神经外科耐碳青霉烯类肺炎克雷伯菌(CRKP)感染患者的临床特点及其经济负担.方法选取2018年1月—2019年10月某三甲医院收治的神经外科患者为研究对象,比较分析CRKP感染患者的基本情况以及住院费用与住院天数.结果神经外科CRKP感染患者多为中老年男性,格拉斯哥昏迷指数(GCS)普遍较低.感染组患者在治疗过程中进行气管切开、机械通气操作的例数较多,住院总费用为136247.45元;非感染组患者费用47979.24元.CRKP肺部感染经济负担为88268.21元,CRKP感染延长了神经外科患者的住院时间22.37 d.结论神经外科CRKP感染患者比非感染患者的GCS低,住院天数延长,经济负担加重,治疗过程中采用气管切开、机械通气等有创性操作增加了感染风险.

Objective To analyze the clinical characteristics and economic burden of patients with carbapenemresistant Klebsiella pneumoniae(CRKP)infection in neurosurgery of a tertiary hospital.Methods The neurosurgical patients admitted to a tertiary hospital from January 2018 to October 2019 were selected as the research objects to compare and analyze the basic conditions of patients with CRKP infection,as well as hospitalization cost and length of stay.Results Most patients with CRKP infection in neurosurgery were middleaged and elderly males,and the Glasgow Coma Scale(GCS)was generally low.In the infected group,there were more cases of tracheotomy and mechanical ventilation during the treatment and the total hospitalization cost was 136247.45 yuan;the cost in the noninfected group was 47979.24 yuan.The economic burden of CRKP pulmonary infection was 88268.21 yuan,and CRKP infection prolonged the length of stay of neurosurgical patients by 22.37 days.Conclusion CRKPinfected patients in neurosurgery have lower GCS,longer length of stay and more economic burden than noninfected patients.Invasive operations such as tracheotomy and mechanical ventilation during the treatment increase the risk of infection.