肺表面活性物质联合无创呼吸机治疗重症肺炎的效果

Effectiveness of pulmonary surfactant combined with non-invasive ventilator therapy on patients with severe pneumonia

目的:探讨肺表面活性物质(PS)联合无创呼吸机治疗重症肺炎的效果。方法:抽取2019年7月至2020年9月长治市第一人民医院收治的足月重症肺炎患儿100例,根据治疗方式分为两组,每组50例。对照组行无创呼吸机治疗,观察组行无创呼吸机联合PS治疗,回顾性统计两组疗效、血气分析指标及并发症。结果:治疗后,观察组胸部X线图像恢复正常者占90.00%(45/50),对照组占70.00%(35/50)。治疗后,观察组氧分压、氧饱和度水平高于对照组(t=1.945、0.631,P<0.05),二氧化碳分压水平低于对照组(t=5.174,P<0.05)。观察组症状消失时间、溶血性链球菌感染发生率少于对照组(t=19.774、χ^(2)=7.111,P<0.05)。结论:PS联合无创呼吸机治疗重症肺炎可快速改善症状,且安全性较高。

Objective To investigate the effectiveness of pulmonary surfactant combined with non-invasive ventilator therapy on patients with severe pneumonia.Methods A total of 100 full-term children with severe pneumonia admitted to Changzhi First People’s Hospital from July 2019 to September 2020 were selected and divided into two groups according to the treatment method,with 50 cases in each group.The control group received non-invasive ventilator therapy,and the observation group received non-invasive ventilator combined with PS therapy.The curative effect,blood gas analysis indexes and complications in the two groups were retrospectively counted.Results After treatment,90.00%(45/50)of the chest X-ray images in the observation group returned to normal,and 70.00%(35/50)in the control group.After treatment,the oxygen partial pressure and oxygen saturation levels in the observation group were higher than those in the control group(t=1.945,0.631,P<0.05),and the partial pressure of carbon dioxide level was lower than that in the control group(t=5.174,P<0.05).The disappearance time of symptoms and the incidence of hemolytic streptococcus infection in the observation group were less than those in the control group(t=19.774,χ^(2)=7.111,P<0.05).Conclusions The treatment of severe pneumonia with PS combined with non-invasive ventilator can quickly improve the symptoms and is safe.