磁共振动态增强扫描联合多b值DWI诊断乳腺疾病临床价值

The application of DCE-MRI combined with multiple-b value DWI in breast benign and malignant diseases

目的探讨磁共振动态增强扫描(DCE-MRI)与多b值弥散加权成像(DWI)成像对乳腺疾病的诊断价值。方法对我院76例乳腺疾病患者,行3.0T DCE-MRI及多b值DWI扫描,并以手术病理或穿刺活检结果为金标准作对照,对比评价DCE-MRI联合多b值DWI对乳腺病变的诊断价值。结果76例乳腺病变患者中病理证实良性病变患者26例,恶性病变患者50例。共检出病灶116个,其中良性病灶34个,恶性病灶82个。DCE-MRI正确诊断良性病灶30个,恶性病灶71个。DCE-MR联合DWI正确诊断良性病灶31个,恶性病灶75个。DCE-MRI联合DWI诊断的准确性为91.38%,敏感性为94.67%,特异性为81.58%,阳性预测值为91.46%,阴性预测值91.18%。仅行DCE-MRI其准确性为87.07%,敏感性为94.67%,特异性为73.17%,阳性预测值86.58%,阴性预测值88.24%。结论DCE-MRI联合多b值DWI扫描比仅行DCE-MRI对良、恶性病灶诊断的准确率明显提高,差异具有统计学意义(P<0.05)。