调督安神针法结合中药方剂治疗围绝经期失眠患者临床研究

Clinical Study on Tiaodu Anshen Needling Method Combined with Chinese Medicine Prescription for Insomnia During Perimenopausal Period

目的:观察调督安神针法结合中药方剂治疗围绝经期失眠患者的临床疗效。方法:选择96例围绝经期失眠患者,按照随机数字表法分为对照组与观察组,各48例。对照组采用滋肾解郁安神方治疗,观察组采用滋肾解郁安神方联合调督安神针法治疗。比较2组治疗前后睡眠质量、临床症状、生活质量评分及性激素水平,并对2组失眠复发率进行比较。结果:与同组治疗前比较,治疗后2组匹兹堡睡眠质量指数评分量表(PSQI)、Kupperman、围绝经期生活质量评定量表(MENQOL)评分及卵泡刺激素(FSH)、黄体生成素(LH)水平均降低(P<0.05),雌二醇(E_(2))水平均升高(P<0.05);与对照组治疗后比较,观察组治疗后PSQI、Kupperman、MENQOL评分及FSH、LH水平均较低(P<0.05),E_(2)水平较高(P<0.05)。观察组复发率为12.50%,对照组复发率为31.25%,2组比较,差异有统计学意义(P<0.05)。结论:调督安神针法结合中药方剂治疗围绝经期失眠患者,有利于改善其睡眠质量、围绝经期综合征症状、机体性激素水平,提高生活质量,并降低失眠复发率。

Objective:To observe the clinical effect of Tiaodu Anshen needling method combined with Chinese medicine prescription on patients with insomnia during perimenopausal period.Methods:A total of 96 cases of patients with insomnia during perimenopausal period were selected and divided into the control group and the observation group according to the random number table method,48 cases in each group.The control group was given Zishen Jieyu Anshen prescription,and the observation group was additionally treated with Tiaodu Anshen needling method based on the treatment of the control group.Before and after treatment,sleep quality,clinical symptoms,score of quality of life,and levels of sex hormones were compared between the two groups.The recurrence rate of insomnia was compared between the two groups.Results:When compared with those before treatment in the same group,scores of Pittsburgh Sleep Quality Index(PSQI),Kupperman,and scale of Menopause-Specific Quality of Life(MENQOL),as well as levels of follicle-stimulating hormones(FSH)and luteinizing hormone(LH)in the two groups were decreased after treatment(P<0.05),and levels of estradiol(E_(2))were increased(P<0.05).After treatment,when compared with those in the control group,scores of PSQI,Kupperman and MENQOL,as well as levels of FSH and LH in the observation group were lower(P<0.05),and level of E_(2) was higher(P<0.05).The recurrence rate was 12.50%in the observation group and 31.25%in the control group,the difference being significant(P<0.05).Conclusion:In the treatment of patients with insomnia during perimenopausal period,the therapy of Tiaodu Anshen needling method combined with Chinese medicine prescription conduces to improving their sleep quality,symptoms of perimenopausal syndrome,levels of sex hormones,and quality of life,and reducing recurrence rate of insomnia.